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2.5.1.46: deoxyhypusine synthase

This is an abbreviated version!
For detailed information about deoxyhypusine synthase, go to the full flat file.

Word Map on EC 2.5.1.46

Reaction

dehydrospermidine
+
[enzyme]-lysine
=
N-(4-aminobutylidene)-[enzyme]-lysine
+
propane-1,3-diamine

Synonyms

CpDHS, deoxyhypusine synthase, deoxyhypusine synthase (Caulobacter crescentus gene CC0359), deoxyhypusine synthase (Halobacterium strain NRC-1 gene dhs), deoxyhypusine synthase (human clone 30649 gene DHPS subunit reduced), deoxyhypusine synthase (Nicotiana tabacum gene DHS1), deoxyhypusine synthase (Senecio vernalis gene DHS1), deoxyhypusinesynthase, DHPS, DHS, DHS1, DHS2, DHS20, DHS34, DHSc, DHSp, DHYS, Dys1, Dys1p, EC 1.1.1.249, HVO 2297, PF3D7_1412600, speY, synthase, deoxyhypusine, TbDHSc, TbDHSp

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.46 deoxyhypusine synthase

Molecular Weight

Molecular Weight on EC 2.5.1.46 - deoxyhypusine synthase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
137000
144000
gel filtration
144000 - 180000
-
gel filtration, sedimentation equilibrium centrifugation
150000
-
gel filtration
165000 - 172000
-
gel filtration sedimentation equilibrium centrifugation
170000
recombinant enzyme, native PAGE
180000
180000 - 190000
-
gel filtration
190000
gel filtration
40000
4 * 40000, SDS-PAGE
40800
41000
41400
-
x * 41400, about, sequence calculation
42000
predicted from cDNA
42074
4 * 42074, calculation from amino acid sequence
42200
42300
43000
44000
x * 44000, recombinant His-tagged enzyme, SDS-PAGE
48000
66000
predicted from cDNA
73000
2 * 66000, about, DHS34, sequence calculation, 2 * 73000, recombinant His-tagged DHS34, SDS-PAGE