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2.5.1.48: cystathionine gamma-synthase

This is an abbreviated version!
For detailed information about cystathionine gamma-synthase, go to the full flat file.

Word Map on EC 2.5.1.48

Reaction

O4-succinyl-L-homoserine
+
L-cysteine
=
L-cystathionine
+
succinate

Synonyms

AtCGS, CGS, CGS1, CS,26, cystathionine gamma-synthase, cystathionine synthase, cystathionine synthetase, cystathionine-gamma-synthase, EC 4.2.99.9, homoserine O-transsuccinylase, homoserine transsuccinylase, HTS, MetB, O-succinyl-L-homoserine succinate-lyase (adding cysteine), O-succinylhomoserine (Thiol)-lyase, O-succinylhomoserine synthase, O-succinylhomoserine synthetase, synthase, cystathionine gamma-

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.48 cystathionine gamma-synthase

KM Value

KM Value on EC 2.5.1.48 - cystathionine gamma-synthase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2.6
2-mercaptoethanol
-
-
100
CH3SH
-
pH 7.3, 30°C, gamma-replacement reaction
3
H2S
-
pH 7.3, 30°C, gamma-replacement reaction
0.11 - 2.4
L-cystathionine
0.1 - 4.07
L-cysteine
0.89
L-cysteine methyl ester
-
-
0.07
L-selenocysteine
-
-
64.5
O-acetyl-L-homoserine
1.4 - 7.1
O-phospho-L-homoserine
2.85
O-phospho-L-serine
-
-
0.05 - 90
O-succinyl-L-homoserine
0.7 - 1.2
O-Succinyl-L-serine
0.6
S2-
-
pH 7.5, 30°C
0.55
Sodium sulfide
-
-
additional information
additional information
-