2.5.1.48: cystathionine gamma-synthase
This is an abbreviated version!
For detailed information about cystathionine gamma-synthase, go to the full flat file.
Word Map on EC 2.5.1.48
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2.5.1.48
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homocystinuria
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transsulfuration
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beta-lyase
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gamma-lyase
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sulfhydrylase
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o-acetylhomoserine
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gamma-replacement
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l-cystathionine
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cystathionase
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o-phosphohomoserine
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paucicostata
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gamma-elimination
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homocystine
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s-methylmethionine
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remethylation
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synthesis
- 2.5.1.48
- homocystinuria
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transsulfuration
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beta-lyase
-
gamma-lyase
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sulfhydrylase
- o-acetylhomoserine
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gamma-replacement
- l-cystathionine
- cystathionase
- o-phosphohomoserine
- paucicostata
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gamma-elimination
- homocystine
- s-methylmethionine
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remethylation
- synthesis
Reaction
Synonyms
AtCGS, CGS, CGS1, CS,26, cystathionine gamma-synthase, cystathionine synthase, cystathionine synthetase, cystathionine-gamma-synthase, EC 4.2.99.9, homoserine O-transsuccinylase, homoserine transsuccinylase, HTS, MetB, O-succinyl-L-homoserine succinate-lyase (adding cysteine), O-succinylhomoserine (Thiol)-lyase, O-succinylhomoserine synthase, O-succinylhomoserine synthetase, synthase, cystathionine gamma-
ECTree
Advanced search results
KM Value
KM Value on EC 2.5.1.48 - cystathionine gamma-synthase
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100
CH3SH
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pH 7.3, 30°C, gamma-replacement reaction
3
H2S
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pH 7.3, 30°C, gamma-replacement reaction
0.11
L-cysteine
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pH 7.8, 25°C, replacement reaction, modified ping-pong mechanism
0.05
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pH 7.3, 30°C, reaction with H2S
0.07
O-succinyl-L-homoserine
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pH 7.3, 30°C, gamma-replacement reaction
0.3
O-succinyl-L-homoserine
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pH 7.3, 30°C, gamma-elimination reaction
1.2
O-succinyl-L-homoserine
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pH 7.8, 25°C, replacement reaction, ordered mechanism
1.3
O-succinyl-L-homoserine
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pH 7.8, 25°C, elimination reaction, modified ping-pong mechanism
1.5
O-succinyl-L-homoserine
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mutant D45F/E325Y, gamma-elimination, 25°C, pH 7.8
2.5
O-succinyl-L-homoserine
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pH 7.8, 25°C, replacement reaction, modified ping-pong mechanism
4
O-succinyl-L-homoserine
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pH 7.3, 30°C, gamma-replacement reaction
9
O-succinyl-L-homoserine
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pH 7.3, 30°C, reaction wirh CH3SH
0.7
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final, inhibited reaction phase
1.2
O-Succinyl-L-serine
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initial reaction phase
additional information
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kinetic analysis of the reaction O-succinyl-L-homoserine + beta-mercaptopropionate
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additional information
additional information
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detailed kinetics of elimination and replacement reaction, overview
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