2.5.1.56: N-acetylneuraminate synthase
This is an abbreviated version!
For detailed information about N-acetylneuraminate synthase, go to the full flat file.
Word Map on EC 2.5.1.56
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2.5.1.56
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n-acetylmannosamine
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antifreeze
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mannac
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meningitidis
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polysialic
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neunacs
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neuroinvasive
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synthesis
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cmp-sialic
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2-epimerase
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ice-binding
- 2.5.1.56
- n-acetylmannosamine
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antifreeze
- mannac
- meningitidis
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polysialic
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neunacs
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neuroinvasive
- synthesis
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cmp-sialic
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2-epimerase
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ice-binding
Reaction
Synonyms
(NANA) condensing enzyme, EC 4.1.3.19, N-acetylneuraminate lyase synthase, N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating), N-acetylneuraminic acid condensing enzyme, N-acetylneuraminic acid synthase, NANA condensing enzyme, NANA synthase, NANAS, NANS, NeuAc synthase, NeuB, NeuB1, NeuNAc synthase, NmeNANAS, sialic acid synthase, synthase, N-acetylneuraminate
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 2.5.1.56 - N-acetylneuraminate synthase
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REACTION DIAGRAM
phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O
N-acetylneuraminate + phosphate
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the neuB genes appear to be involved in the biosynthesis of at least two distinct surface structures: lipooligosaccharide and flagella
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N-acetyl-D-mannosamine + phosphoenolpyruvate + H2O
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the neuB genes appear to be involved in the biosynthesis of at least two distinct surface structures: lipooligosaccharide and flagella
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N-acetyl-D-mannosamine + phosphoenolpyruvate + H2O
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the enzyme is necessary for the synthesis of N-acetylneuraminate which is required for synthesis of the capsular polysaccharide alpha(2-8)poly-N-acetylneuraminic acid. This polysaccharide is an essential virulence factor of the neuropathogenic bacteria
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N-acetyl-D-mannosamine + phosphoenolpyruvate + H2O
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the enzyme is necessary for the synthesis of N-acetylneuraminate which is required for synthesis of the capsular polysaccharide alpha(2-8)poly-N-acetylneuraminic acid. This polysaccharide is an essential virulence factor of the neuropathogenic bacteria
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N-acetyl-D-mannosamine + phosphoenolpyruvate + H2O
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the enzyme is involved in sialic acid synthesis
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N-acetyl-D-mannosamine + phosphoenolpyruvate + H2O
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the enzyme is involved in sialic acid synthesis
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N-acetyl-D-mannosamine + phosphoenolpyruvate + H2O
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the enzyme is involved in sialic acid synthesis
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phosphate + N-acetylneuraminate
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ir
phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O
phosphate + N-acetylneuraminate
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ir
phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O
phosphate + N-acetylneuraminate
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phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O
phosphate + N-acetylneuraminate
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phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O
phosphate + N-acetylneuraminate
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phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O
phosphate + N-acetylneuraminate
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