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2.5.1.58: protein farnesyltransferase

This is an abbreviated version!
For detailed information about protein farnesyltransferase, go to the full flat file.

Word Map on EC 2.5.1.58

Reaction

farnesyl diphosphate
+
protein-cysteine
=
S-farnesyl protein
+
diphosphate

Synonyms

AfFTase, CAAX farnesyltransferase, EhFT, Era1, farnesyl protein transferase, farnesyltransferase, farnesyltransferase ternary complex part II, farnesyltransferase, farnesyl pyrophosphate-protein, farnesyltransferase, protein, FntA, FntB, FPT, fptase, FTase, hFTase, HIT5, Pf-PFT, PfPFT, PFT, PFTase, prenyl transferase, prenylprotein transferase, prenyltransferase, protein cysteine farnesyltransferase, protein farnesyl transferase, protein farnesyltransferase, protein prenyltransferase, protein-farnesyltransferase, R-PFT, Ram1, RAS farnesyltransferase, Ras protein farnesyltransferase, rFPTase, rFTase, rPFTase, TbFTase, yPFTase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.58 protein farnesyltransferase

Cloned

Cloned on EC 2.5.1.58 - protein farnesyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
coexpression of alpha and beta subunits of enzyme by Sf9 cells infected with a recombinant baculovirus
coexpression of alpha and beta subunits of enzyme with a recombinant baculovirus
-
enzyme produced using an Sf9 cell overexpression
expressed in baculovirus
-
expressed in Escherichia coli
-
expressed in Escherichia coli BL21(DE3) FPT/pET23a cells
-
expressed in Escherichia coli BL21(DE3)/pRD57 cells
-
expressed in Saccharomyces cerevisiae
-
expression in bloodstream and insect stage parasites, and expression in Escherichia coli
-
expression in Escherichia coli
expression in Escherichia coli BL 21
-
expression in Escherichia coli BL21
-
in transgenic canola lines
-
recombinant alpha- and beta-subunits, coexpressed in Escherichia coli, form a heterodimer and show activity to transfer farnesyl using farnesylpyrophosphate as a donor to human H-Ras possessing a C-terminal CVLS, but not a mutant H-Ras possessing CVLL.
translationally coupled two-cistron expression system for enzyme in Escherichia coli
-
wild-type enzyme and mutant enzymes expressed in Escherichia coli
-