2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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For detailed information about UDP-N-acetylglucosamine 1-carboxyvinyltransferase, go to the full flat file.

Word Map on EC 2.5.1.7

2.5.1.7

peptidoglycan

fosfomycin

pep

cloacae

enterobacter

medicine

epsps

drug development

5-enolpyruvylshikimate

sanguinis

5-enolpyruvylshikimate-3-phosphate

Reaction

UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine

Synonyms

enol-pyruvyltransferase, enolpyruvyl UDP-GlcNAc synthase, enoylpyruvate transferase, enoylpyruvatetransferase, EPT, More, MurA, MurA enzyme, MurA transferase, MurAA, MurZ, phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase, phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase, phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase, phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose-3-enolpyruvyltransferase, phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase, pyruvate-UDP-acetylglucosamine transferase, pyruvate-uridine diphospho-N-acetyl-glucosamine transferase, pyruvate-uridine diphospho-N-acetylglucosamine transferase, pyruvatetransferase, phosphoenolpyruvate-uridine diphosphoacetylglucosamine, pyruvic-uridine diphospho-N-acetylglucosaminyltransferase, UDP-GlcNAc enolpyruvyl transferase, UDP-N-acetylglucosamine 1-carboxyvinyl transferase, UDP-N-acetylglucosamine 1-carboxyvinyl-transferase, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, UDP-N-acetylglucosamine enolpyruvyl transferase, UDP-N-acetylglucosamine enolpyruvyle transferase, UDP-N-acetylglucosamine enolpyruvyltransferase, UDP-N-acetylglucosamine enoylpyruvyltransferase, UDP-N-acetylglucosamine-enolpyruvyl transferase, UDP-NAG enolpyruvyl transferase, UNAG enolpyruvyl transferase

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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Results	in table
4	Activating Compound
45128	AA Sequence
12	Application
1	CAS Registry Number
33	Cloned(Commentary)
12	Crystallization (Commentary)
29	General Information
3	General Stability
71	IC50 Value
374	Inhibitors
21	kcat/KM [mM/s]
38	Ki Value [mM]
50	KM Value [mM]
2	Localization
6	Metals/Ions
21	Molecular Weight [Da]
40	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
387	Organism
9	Pathway
166	PDB ID
13	pH Optimum
4	pH Range
1	pI Value
56	Protein Variants
31	Purification (Commentary)
37	Reaction
1	Reaction Type
104	Reference
10	Specific Activity [micromol/min/mg]
7	Storage Stability
115	Substrates and Products (Substrate)
24	Subunits
126	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
32	Turnover Number [1/s]

KI Value

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KI Value on EC 2.5.1.7 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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0.04 - 0.1

(Z)-3-fluorophosphoenolpyruvate

6 entries

0.0086 - 2

fosfomycin

5 entries

0.05109

orientin

Fusobacterium nucleatum subsp. nucleatum

Q8RIQ1

pH 7.5, 37°C

759755

0.038

PGE-553828

Escherichia coli

637606

1.7

phosphoenol-2-ketovalerate

Enterobacter cloacae

637594

0.00953

quercetin-3-O-D-glucuronide

Fusobacterium nucleatum subsp. nucleatum

Q8RIQ1

pH 7.5, 37°C

759755

0.016

T6362

Enterobacter cloacae

P33038

20°C, pH 8.0

659457

4.9 - 6.6

UDP-N-acetylmuramyl-L-Ala-D-Glu-meso-alpha,epsilon-diaminopimelic acid

Enterobacter cloacae

637588

0.8

uridine diphospho-N-acetylmuramyl-L-Ala-D-gamma-Glu-meso-alpha,epsilon-diaminopimelic-acid-D-Ala-D-Ala

Enterobacter cloacae

637588

0.00013367

ZINC11784805