2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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For detailed information about UDP-N-acetylglucosamine 1-carboxyvinyltransferase, go to the full flat file.

Reaction

Synonyms

enol-pyruvyltransferase, enolpyruvyl UDP-GlcNAc synthase, enoylpyruvate transferase, enoylpyruvatetransferase, EPT, More, MurA, MurA enzyme, MurA transferase, MurAA, MurZ, phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase, phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase, phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase, phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose-3-enolpyruvyltransferase, phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase, pyruvate-UDP-acetylglucosamine transferase, pyruvate-uridine diphospho-N-acetyl-glucosamine transferase, pyruvate-uridine diphospho-N-acetylglucosamine transferase, pyruvatetransferase, phosphoenolpyruvate-uridine diphosphoacetylglucosamine, pyruvic-uridine diphospho-N-acetylglucosaminyltransferase, UDP-GlcNAc enolpyruvyl transferase, UDP-N-acetylglucosamine 1-carboxyvinyl transferase, UDP-N-acetylglucosamine 1-carboxyvinyl-transferase, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, UDP-N-acetylglucosamine enolpyruvyl transferase, UDP-N-acetylglucosamine enolpyruvyle transferase, UDP-N-acetylglucosamine enolpyruvyltransferase, UDP-N-acetylglucosamine enoylpyruvyltransferase, UDP-N-acetylglucosamine-enolpyruvyl transferase, UDP-NAG enolpyruvyl transferase, UNAG enolpyruvyl transferase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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Results	in table
4	Activating Compound
45128	AA Sequence
12	Application
1	CAS Registry Number
33	Cloned(Commentary)
12	Crystallization (Commentary)
29	General Information
3	General Stability
71	IC50 Value
374	Inhibitors
21	kcat/KM [mM/s]
38	Ki Value [mM]
50	KM Value [mM]
2	Localization
6	Metals/Ions
21	Molecular Weight [Da]
40	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
387	Organism
9	Pathway
166	PDB ID
13	pH Optimum
4	pH Range
1	pI Value
56	Protein Variants
31	Purification (Commentary)
37	Reaction
1	Reaction Type
104	Reference
10	Specific Activity [micromol/min/mg]
7	Storage Stability
115	Substrates and Products (Substrate)
24	Subunits
126	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
32	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 2.5.1.7 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-15°C, crude enzyme preparation, in presence of 4 mM DTT, loss of 84% activity within 2 weeks

Staphylococcus epidermidis

-

637591

-196°C, 4 mM DTT, stable for up to 6 weeks, partially purified enzyme

Staphylococcus epidermidis

-

637591

-196°C, slightly increased activity after storage of 2 weeks

Staphylococcus epidermidis

-

637591

-20°C, loss of activity after 1 week

Enterobacter cloacae

-

637588

-70°C, 4 mM DTT, 22% loss of activity in 2 weeks, partially purified enzyme

Staphylococcus epidermidis

-

637591

0°C or -20°C, 0.2 mg/ml DTT, 40% loss of activity after 2 weeks

Enterobacter cloacae

-

637587

4°C, in 80% ammonium sulfate, loss of activity after 1 week

Enterobacter cloacae

-

637588