2.5.1.92: (2Z,6Z)-farnesyl diphosphate synthase

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For detailed information about (2Z,6Z)-farnesyl diphosphate synthase, go to the full flat file.

Reaction

Synonyms

cis,cis-farnesyl diphosphate synthase, cis-prenyltransferase, CPT1, FPPase, IDS3, More, short-chain cis-prenyldiphosphate synthase, short-chain SlCPT, SlCPT6, trans-isoprenyl diphosphate synthase, Z,Z-farnesyl diphosphate synthase, Z,Z-farnesyl pyrophosphate synthase, Z,Z-FPP synthase, zFPS

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.92 (2Z,6Z)-farnesyl diphosphate synthase

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Results	in table
3	AA Sequence
2	Application
5	Cloned(Commentary)
2	Crystallization (Commentary)
7	General Information
2	Inhibitors
7	kcat/KM [mM/s]
1	Ki Value [mM]
13	KM Value [mM]
3	Localization
2	Metals/Ions
2	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
11	Organism
3	Pathway
8	PDB ID
3	pH Optimum
5	Protein Variants
5	Purification (Commentary)
1	Reaction
10	Reference
12	Source Tissue
23	Substrates and Products (Substrate)
3	Subunits
23	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
7	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.5.1.92 - (2Z,6Z)-farnesyl diphosphate synthase

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SYSTEMATIC NAME

IUBMB Comments

dimethylallyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 2 isopentenyl units)

This enzyme, originally characterized from wild tomato, specifically forms (2Z,6Z)-farnesyl diphosphate via neryl diphosphate and isopentenyl diphosphate. In wild tomato it is involved in the biosynthesis of several sesquiterpenes. See also EC 2.5.1.68 [(2Z,6E)-farnesyl diphosphate synthase] and EC 2.5.1.10 [(2E,6E)-farnesyl diphosphate synthase].