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2.5.1.94: adenosyl-chloride synthase

This is an abbreviated version!
For detailed information about adenosyl-chloride synthase, go to the full flat file.

Word Map on EC 2.5.1.94

Reaction

S-adenosyl-L-methionine
+
chloride
=
5-deoxy-5-chloroadenosine
 +
L-methionine

Synonyms

5'-chloro-5'-deoxyadenosine synthase, AclH, chlorinase, Cla1, ClA2, S-adenosyl-L-methionine-dependent chlorinase, SalL, SAM-dependent chlorinase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.94 adenosyl-chloride synthase

KCat KM Value

KCat KM Value on EC 2.5.1.94 - adenosyl-chloride synthase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1000
5'-chloro-5'-deoxyadenosine
in 50 mM phosphate buffer (pH 7.9) at 37°C
181.1
5'-deoxy-5'-iodoadenosine
in 50 mM phosphate buffer (pH 7.9) at 37°C
0.035
5-deoxy-5'-bromoadenosine
37°C, direct displacement reaction in the absence of L-methionine or S-adenosyl-L-methionine, pH not specified in the publication
14.89 - 26.29
5-deoxy-5'-chloroadenosine
14.89 - 26.29
5-deoxy-5-chloroadenosine
0.0000883
bromide
in 50 mM phosphate buffer (pH 7.9) at 37°C
0.0003
chloride
in 50 mM phosphate buffer (pH 7.9) at 37°C
0.0000192
Iodide
in 50 mM phosphate buffer (pH 7.9) at 37°C
0.077
L-methionine
in 50 mM phosphate buffer (pH 7.9) at 37°C
4.5 - 15
S-adenosyl-L-methionine