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2.6.1.105: lysine-8-amino-7-oxononanoate transaminase

This is an abbreviated version!
For detailed information about lysine-8-amino-7-oxononanoate transaminase, go to the full flat file.

Reaction

L-lysine
+
8-Amino-7-oxononanoate
=
(S)-2-amino-6-oxohexanoate
+
7,8-diaminononanoate

Synonyms

bioA, bioK, DAPA aminotransferase

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.105 lysine-8-amino-7-oxononanoate transaminase

Systematic Name

Systematic Name on EC 2.6.1.105 - lysine-8-amino-7-oxononanoate transaminase

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SYSTEMATIC NAME
IUBMB Comments
L-lysine:8-amino-7-oxononanoate aminotransferase
A pyridoxal 5'-phosphate enzyme [2]. Participates in the pathway for biotin biosynthesis. The enzyme from the bacterium Bacillus subtilis cannot use S-adenosyl-L-methionine as amino donor and catalyses an alternative reaction for the conversion of 8-amino-7-oxononanoate to 7,8-diaminononanoate (cf. EC 2.6.1.62, adenosylmethionine---8-amino-7-oxononanoate transaminase).