2.6.1.13: ornithine aminotransferase
This is an abbreviated version!
For detailed information about ornithine aminotransferase, go to the full flat file.
Word Map on EC 2.6.1.13
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2.6.1.13
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atrophy
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gyrate
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arginase
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retina
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choroid
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pyridoxal
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polyamines
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chorioretinal
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hyperornithinemia
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citrulline
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putrescine
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transamination
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aminotransferases
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delta1-pyrroline-5-carboxylate
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1-pyrroline-5-carboxylate
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argininosuccinate
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gabaculine
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hyperammonemias
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carbamoylphosphate
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biotechnology
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medicine
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plp-dependent
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analysis
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drug development
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diagnostics
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agriculture
- 2.6.1.13
- atrophy
-
gyrate
- arginase
- retina
- choroid
- pyridoxal
- polyamines
-
chorioretinal
-
hyperornithinemia
- citrulline
- putrescine
-
transamination
- aminotransferases
- delta1-pyrroline-5-carboxylate
- 1-pyrroline-5-carboxylate
- argininosuccinate
- gabaculine
-
hyperammonemias
- carbamoylphosphate
- biotechnology
- medicine
-
plp-dependent
- analysis
- drug development
- diagnostics
- agriculture
Reaction
Synonyms
aminotransferase, ornithine-keto acid, delta OAT, delta-OAT, delta-ornithine aminotransferase, deltaOAT, EC 2.6.1.68, hOAT, L-ornithine 5-aminotransferase, L-ornithine aminotransferase, L-ornithine:2-oxoacid aminotransferase, L-ornithine:alpha-ketoglutarate delta-aminotransferase, OAT, Orn-AT, ornithine 5-aminotransferase, ornithine amino transferase, ornithine aminotransferase, ornithine delta aminotransferase, ornithine delta-amino transferase, ornithine delta-aminotransferase, ornithine delta-transaminase, ornithine transaminase, ornithine-2-oxoacid aminotransferase, ornithine-alpha-ketoglutarate aminotransferase, ornithine-delta-aminotransferase, ornithine-keto acid aminotransferase, ornithine-keto acid transaminase, ornithine-ketoglutarate aminotransferase, ornithine-oxo acid aminotransferase, ornithine-oxo-acid transaminase, ornithine: 2-oxo-glutarate aminotransferase, ornithine:alpha-oxoglutarate transaminase, PsOAT, RocD, TaOAT, TaOAT-5AL, TaOAT-5B, TaOAT-5BL, TaOAT-5DL, TaOAT-AL-2, TgOAT
ECTree
2.6.1.13 ornithine aminotransferaseAdvanced search results
results (
results (KM Value
KM Value on EC 2.6.1.13 - ornithine aminotransferase
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.15
2-oxoglutarate
pH and temperature not specified in the publication, liver isolated mitochondria
0.65
2-oxoglutarate
pH and temperature not specified in the publication
0.72
2-oxoglutarate
pH and temperature not specified in the publication, liver enzyme
0.73
2-oxoglutarate
pH and temperature not specified in the publication, liver enzyme
0.75
2-oxoglutarate
pH and temperature not specified in the publication
0.88
2-oxoglutarate
pH and temperature not specified in the publication, liver enzyme
0.91
2-oxoglutarate
pH and temperature not specified in the publication, kidney enzyme
0.95
2-oxoglutarate
pH and temperature not specified in the publication, small intestine enzyme
1.2
2-oxoglutarate
wild-type (OAT in parasite cell extract), pH 7.4, 37°C
1.3
2-oxoglutarate
pH and temperature not specified in the publication, eye enzyme
2.6
2-oxoglutarate
pH and temperature not specified in the publication, brain enzyme
2.75
2-oxoglutarate
pH and temperature not specified in the publication, eye iris enzyme
3.9
2-oxoglutarate
pH 8.0, 25°C, recombinant wild-type enzyme, 60 nM enzyme
4
2-oxoglutarate
pH 8.0, 15°C, recombinant wild-ype enzyme, 0.001 mM enzyme
4.4
2-oxoglutarate
pH 8.0, 15°C, recombinant mutant R217A, 0.001 mM enzyme
0.56 - 2.8
L-ornithine
pH and temperature not specified in the publication, liver enzyme
0.59
L-ornithine
pH and temperature not specified in the publication, kidney enzyme
0.6
L-ornithine
pH and temperature not specified in the publication, small intestine enzyme
0.8
L-ornithine
pH and temperature not specified in the publication, enzyme from cortical interneurons
1.1
L-ornithine
pH and temperature not specified in the publication, brain enzyme
1.2 - 4.8
L-ornithine
pH and temperature not specified in the publication, liver enzyme
2.089
L-ornithine
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in rat brain mitochondrial fraction, in absence of pyridoxal 5'-phosphate
2.3
L-ornithine
wild-type (OAT in parasite cell extract), pH 7.4, 37°C
3.7
L-ornithine
pH and temperature not specified in the publication, eye retina enzyme
3.95
L-ornithine
pH and temperature not specified in the publication
4
L-ornithine
pH and temperature not specified in the publication, liver isolated mitochondria
4.3
L-ornithine
pH and temperature not specified in the publication, enzyme from astrocytes
4.7
L-ornithine
pH and temperature not specified in the publication, enzyme from cerebellar granule cells
5.089
L-ornithine
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in rat brain mitochondrial fraction, in presence of 0.05 mM pyridoxal 5'-phosphate
5.6
L-ornithine
pH and temperature not specified in the publication, eye enzyme
7
L-ornithine
pH 8.0, 15°C, recombinant wild-type enzyme, 0.001 mM enzyme
7.5
L-ornithine
pH and temperature not specified in the publication, liver enzyme
10.5
L-ornithine
assay based on reduction of DELTA1-pyrroline-5-carboxylate, pH 8.0, 37°C
additional information
additional information
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aggregation results in increase of Km
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additional information
additional information
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Km for ornithine increases below pH 7.5, Km for 2-oxoglutarate decreases below pH 7
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additional information
additional information
no Michaelis-Menten kinetics are obtained, possibly a positive cooperative behavior with kinetic values S0.5 of 0.8mM for 2-oxoglutarate and S0.5 of 6.3 mM for ornithine
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additional information
additional information
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no Michaelis-Menten kinetics are obtained, possibly a positive cooperative behavior with kinetic values S0.5 of 0.8mM for 2-oxoglutarate and S0.5 of 6.3 mM for ornithine
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additional information
additional information
Michaelis-Menten steady-state kinetics
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additional information
additional information
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Michaelis-Menten steady-state kinetics
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additional information
additional information
steady-state and pre-steady state Michaelis-Menten kinetics, rapid-scanning stopped-flow kinetics, and transamination half-reaction kinetic parameters, overview
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additional information
additional information
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steady-state and pre-steady state Michaelis-Menten kinetics, rapid-scanning stopped-flow kinetics, and transamination half-reaction kinetic parameters, overview
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