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2.6.1.16: glutamine-fructose-6-phosphate transaminase (isomerizing)

This is an abbreviated version!
For detailed information about glutamine-fructose-6-phosphate transaminase (isomerizing), go to the full flat file.

Word Map on EC 2.6.1.16

Reaction

L-glutamine
+
D-fructose 6-phosphate
=
L-glutamate
+
D-glucosamine 6-phosphate

Synonyms

2-amino-2-deoxy-D-glucose-6-phosphate ketol-isomerase, BsglmS, EC 5.3.1.19, G-6-P synthase, Gfa1, Gfa1p, GFAT, GFAT1, GFAT2, GFPT1, GlcN-6-P synthase, GlmS, glmS ribozyme, glucosamine 6-phosphate synthase, glucosamine 6-phosphate synthetase, glucosamine phosphate isomerase (glutamine-forming), glucosamine synthase, glucosamine-6-P synthase, glucosamine-6-phosphate isomerase (glutamine-forming), glucosamine-6-phosphate synthase, glucosamine-6-phosphate synthetase, glucosamine-6P synthase, glucosamine:fructose-6-phosphate aminotransferase, glutamine-fructose 6-phosphate amidotransferase, glutamine-fructose 6-phosphate aminotransferase, glutamine-fructose-6-phosphate aminotransferase, glutamine-fructose-6-phosphate transaminase 1, glutamine: fructose-6-phosphate amidotransferase, glutamine: fructose-6-phosphate amidotransferase 1, glutamine: fructose-6-phosphate aminotransferase, glutamine:fructose-6-phosphate amidotransferase, glutamine:fructose-6-phosphate aminotransferase, hexosephosphate aminotransferase, isomerase, glucosamine phosphate (glutamine-forming), L-glutamine D-fructose 6-phosphate amidotransferase, L-glutamine fructose 6-phosphate transamidase, L-glutamine: D-fructose-6-phosphate amidotransferase, L-glutamine: L-fructose-6-phosphate amidotransferase, L-glutamine:D-fructose-6-phosphate amidotransferase, L-glutamine:D-fructose-6-phosphate amidotransferase (hexose isomerizing), L-glutamine:D-fructose-6-phosphate amidotransferase (hexose-isomerizing), L-glutamine:L-fructose-6-phosphate amidotransferase

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.16 glutamine-fructose-6-phosphate transaminase (isomerizing)

IC50 Value

IC50 Value on EC 2.6.1.16 - glutamine-fructose-6-phosphate transaminase (isomerizing)

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.66
(2S)-2-amino-3-(([(2R,3R)-3-benzoyloxiran-2-yl]carbonyl)amino)propanoic acid
Saccharomyces cerevisiae
-
pH 7.0, 37°C
0.27
(2S)-2-amino-3-([(2E)-4-oxo-4-phenylbut-2-enoyl]amino)propanoic acid
Saccharomyces cerevisiae
-
pH 7.0, 37°C
5.6
(2S)-2-amino-3-([(2E)-4-oxopent-2-enoyl]amino)propanoic acid
Saccharomyces cerevisiae
-
pH 7.0, 37°C
7.3
(2S)-3-(([(2R,3R)-3-acetyloxiran-2-yl]carbonyl)amino)-2-aminopropanoic acid
Saccharomyces cerevisiae
-
pH 7.0, 37°C
0.0051
1-methyl 8-(2-oxopropyl) (2E,7S)-7-amino-4-oxooct-2-enedioate
Candida albicans
-
pH not specified in the publication, temperature not specified in the publication
0.0049
1-methyl 8-[(2R)-3-oxobutan-2-yl] (2E,7S)-7-amino-4-oxooct-2-enedioate
Candida albicans
-
pH not specified in the publication, temperature not specified in the publication
0.056 - 0.085
2-amino-2-deoxy-D-glucitol-6-phosphate
0.073
2-amino-2-deoxy-D-mannitol 6-phosphate
Sporothrix schenckii
pH not specified in the publication, temperature not specified in the publication
0.0052
8-(3,3-dimethyl-2-oxobutyl) 1-methyl (2E,7S)-7-amino-4-oxooct-2-enedioate
Candida albicans
-
pH not specified in the publication, temperature not specified in the publication
0.12
Aaptamine
Escherichia coli
IC50: 0.12 mM
0.1
amitrole
Escherichia coli
IC50: 0.1 mM
0.081
methyl (2E)-4-([(2S)-2,3-diamino-3-oxopropyl]amino)-4-oxobut-2-enoate
Candida albicans
-
pH 7.0, 37°C
0.127
methyl (2E)-4-([(2S)-2-amino-3-(methylamino)-3-oxopropyl]amino)-4-oxobut-2-enoate
Candida albicans
-
pH 7.0, 37°C
0.013 - 0.12
N3-(4-Methoxyfumaroyl)-L-2,3-diaminopropanoic acid
0.52
UDP-N-acetyl-alpha-D-glucosamine
Saccharomyces cerevisiae
-
pH 7.0, 37°C
0.45
UDP-N-acetylglucosamine
Sporothrix schenckii
crude enzyme preparation, pH not specified in the publication, temperature not specified in the publication
1.55 - 2
uridine 5'-diphospho-N-acetyl-D-glucosamine
0.16
uridine 5'-diphospho-N-acetylglucosamine
Volvariella volvacea
recombinant enzyme, in 10 mM KCl, 1 mg/ml bovine serum albumin, 20 mM imidazole buffer (pH 6.8), 1 mM EDTA, 1 mM dithiothreitol, and 10% (v/v) glycerol