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2.6.1.19: 4-aminobutyrate-2-oxoglutarate transaminase

This is an abbreviated version!
For detailed information about 4-aminobutyrate-2-oxoglutarate transaminase, go to the full flat file.

Word Map on EC 2.6.1.19

Reaction

4-aminobutanoate
+
2-oxoglutarate
=
succinate semialdehyde
 +
L-glutamate

Synonyms

4-aminobutyrate aminotransferase, 4-aminobutyrate transaminase, 4-aminobutyrate-2-ketoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate transaminase, 4-aminobutyric acid 2-ketoglutaric acid aminotransferase, 4-aminobutyric acid aminotransferase, ABAT, aminobutyrate aminotransferase, aminobutyrate transaminase, aminotransferase, aminobutyrate, argD, argD6803, argD7002, Atu3000, beta-alanine aminotransferase, beta-alanine transaminase, beta-alanine-oxoglutarate aminotransferase, beta-alanine-oxoglutarate transaminase, bioA, CG010_026395, CgGABA-AT, GABA aminotransferase, GABA transaminase, GABA transferase, GABA-2-oxoglutarate aminotransferase, GABA-2-oxoglutarate transaminase, GABA-alpha-ketoglutarate aminotransferase, GABA-alpha-ketoglutarate transaminase, GABA-alpha-ketoglutaric acid transaminase, GABA-alpha-oxoglutarate aminotransferase, GABA-AT, GABA-oxoglutarate aminotransferase, GABA-oxoglutarate transaminase, GABA-T, GABA-T1, GABA-T2, GABA-T3, GABA-TA, GABA-transaminase, GABA:2-oxoglutarate aminotransferase, GABAT, GabT, gamma-aminobutyrate aminotransaminase, gamma-aminobutyrate aminotransferase, gamma-aminobutyrate transaminase, gamma-aminobutyrate transaminases, gamma-aminobutyrate-alpha-ketoglutarate aminotransferase, gamma-aminobutyrate-alpha-ketoglutarate transaminase, gamma-aminobutyrate: GABA transaminase, gamma-aminobutyrate:alpha-oxoglutarate aminotransferase, gamma-aminobutyric acid aminotransferase, gamma-aminobutyric acid pyruvate transaminase, gamma-aminobutyric acid transaminase, gamma-aminobutyric acid-2-oxoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase, gamma-aminobutyric transaminase, gatT, glutamate-succinic semialdehyde transaminase, homotaurine:2-oxoglutarate aminotransferase, MdGABA-T1, MdGABA-T2, More, NCgl0462, NCgl2515, Osl2, pollen-pistil incompatibility 2, Pop2, SkUga1p, slr1022

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.19 4-aminobutyrate-2-oxoglutarate transaminase

Molecular Weight

Molecular Weight on EC 2.6.1.19 - 4-aminobutyrate-2-oxoglutarate transaminase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
103000
-
PAGE
105000
107000
109000
-
high speed sedimentation equilibrium centrifugation
110000
-
liver enzyme, gel filtration
110100
-
liver enzyme, crystallographic data
120000
mass of native protein, determined by gel filtration
176000 - 178000
-
gel filtration, sedimentation equilibrium centrifugation
200000
45000
denaturated protein, determined by SDS-PAGE
50000
52000
-
x * 52000, SDS-PAGE, x * 53950, deduced from gene sequence
52700
-
2 * 53300, SDS-PAGE, brain enzyme, 2 * 52700, SDS-PAGE, liver enzyme
53000
-
1 * 53000 + 1 * 58000, SDS-PAGE
53060
-
calculated from sequence of cDNA
53300
-
2 * 53300, SDS-PAGE, brain enzyme, 2 * 52700, SDS-PAGE, liver enzyme
53950
-
x * 52000, SDS-PAGE, x * 53950, deduced from gene sequence
54200
SDS-PAGE, single recombinant truncated MdGABA-T
55000
-
2 * 55000, liver enzyme, SDS-PAGE
56000
2 * 56000, SDS-PAGE
56474
x * 56474, recombinant protein, calculated
57000
58000
-
1 * 53000 + 1 * 58000, SDS-PAGE
97000
additional information
-
compared to liver enzyme, mature form of brain enzyme has an additional peptide at the N-terminus which may be cleaved by liver mitochondrial extract