2.6.1.19: 4-aminobutyrate-2-oxoglutarate transaminase

This is an abbreviated version!
For detailed information about 4-aminobutyrate-2-oxoglutarate transaminase, go to the full flat file.

Word Map on EC 2.6.1.19

2.6.1.19

gabaergic

neurotransmitter

seizure

epilepsy

anticonvulsant

agonist

antiepileptic

aminooxyacetic

gamma-vinyl

dopamine

bicuculline

muscimol

shunt

hypothalamus

neurotransmission

pyridoxal

gabab

convulsion

valproate

gabaculine

excitatory

baclofen

striatum

benzodiazepine

transmitter

synaptosomes

diazepam

transamination

ssadh

gaba-mediated

substantia

picrotoxin

neurochemical

tiagabine

pentylenetetrazol

3hgaba

3-mercaptopropionic

4.1.1.15

homocarnosine

gamma-hydroxybutyrate

silverman

nipecotic

gabapentin

plp-dependent

kindling

electroshock

enzyme-activated

clonic

gaba-induced

ethosuximide

medicine

molecular biology

Reaction

Synonyms

4-aminobutyrate aminotransferase, 4-aminobutyrate transaminase, 4-aminobutyrate-2-ketoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate transaminase, 4-aminobutyric acid 2-ketoglutaric acid aminotransferase, 4-aminobutyric acid aminotransferase, ABAT, aminobutyrate aminotransferase, aminobutyrate transaminase, aminotransferase, aminobutyrate, argD, argD6803, argD7002, Atu3000, beta-alanine aminotransferase, beta-alanine transaminase, beta-alanine-oxoglutarate aminotransferase, beta-alanine-oxoglutarate transaminase, bioA, CG010_026395, CgGABA-AT, GABA aminotransferase, GABA transaminase, GABA transferase, GABA-2-oxoglutarate aminotransferase, GABA-2-oxoglutarate transaminase, GABA-alpha-ketoglutarate aminotransferase, GABA-alpha-ketoglutarate transaminase, GABA-alpha-ketoglutaric acid transaminase, GABA-alpha-oxoglutarate aminotransferase, GABA-AT, GABA-oxoglutarate aminotransferase, GABA-oxoglutarate transaminase, GABA-T, GABA-T1, GABA-T2, GABA-T3, GABA-TA, GABA-transaminase, GABA:2-oxoglutarate aminotransferase, GABAT, GabT, gamma-aminobutyrate aminotransaminase, gamma-aminobutyrate aminotransferase, gamma-aminobutyrate transaminase, gamma-aminobutyrate transaminases, gamma-aminobutyrate-alpha-ketoglutarate aminotransferase, gamma-aminobutyrate-alpha-ketoglutarate transaminase, gamma-aminobutyrate: GABA transaminase, gamma-aminobutyrate:alpha-oxoglutarate aminotransferase, gamma-aminobutyric acid aminotransferase, gamma-aminobutyric acid pyruvate transaminase, gamma-aminobutyric acid transaminase, gamma-aminobutyric acid-2-oxoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase, gamma-aminobutyric transaminase, gatT, glutamate-succinic semialdehyde transaminase, homotaurine:2-oxoglutarate aminotransferase, MdGABA-T1, MdGABA-T2, More, NCgl0462, NCgl2515, Osl2, pollen-pistil incompatibility 2, Pop2, SkUga1p, slr1022

ECTree

2 Transferases

2.6 Transferring nitrogenous groups

2.6.1 Transaminases

2.6.1.19 4-aminobutyrate-2-oxoglutarate transaminase

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Results	in table
1	Activating Compound
11867	AA Sequence
8	Application
1	CAS Registry Number
24	Cloned(Commentary)
57	Cofactor
12	Crystallization (Commentary)
680	Disease/ Diagnostics
7	Expression
85	General Information
3	General Stability
10	IC50 Value
264	Inhibitors
16	kcat/KM [mM/s]
61	Ki Value [mM]
114	KM Value [mM]
35	Localization
3	Metals/Ions
42	Molecular Weight [Da]
59	Natural Substrates/ Products (Substrates)
165	Organism
17	Pathway
105	PDB ID
38	pH Optimum
13	pH Range
4	pH Stability
2	pI Value
48	Protein Variants
26	Purification (Commentary)
10	Reaction
1	Reaction Type
151	Reference
3	Renatured (Commentary)
115	Source Tissue
60	Specific Activity [micromol/min/mg]
5	Storage Stability
275	Substrates and Products (Substrate)
24	Subunits
268	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
6	Temperature Range [°C]
22	Temperature Stability [°C]
46	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.6.1.19 - 4-aminobutyrate-2-oxoglutarate transaminase

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3-aminopropanesulfonate + 2-oxoglutarate

3-sulfopropanal + L-glutamate

Cupriavidus necator

Q0K2K2

substrate is homotaurine

698627

4-aminobutanoate + 2-oxoglutarate

4-oxobutanoate + L-glutamate

15 entries

4-aminobutanoate + 2-oxoglutarate

succinate semialdehyde + L-glutamate

25 entries

4-aminobutanoate + pyruvate

succinate semialdehyde + L-alanine

7 entries

4-aminobutyrate + 2-oxoglutarate

4-oxobutanoate + L-glutamate

Cupriavidus necator

Q0K2K2

698627

4-aminobutyrate + 2-oxoglutarate

succinic semialdehyde + L-glutamate

2 entries

N2-acetyl-L-ornithine + 2-oxoglutarate

N-acetyl-L-glutamate 5-semialdehyde + L-glutamate

2 entries

additional information

Pseudomonas aeruginosa

enzyme is induced in cells grown on 4-guanidinobutyrate, 4-aminobutyrate, or putrescine as the only carbon and nitrogen source. GABAT functions in the biosynthesis of arginine by converting N2-acetyl-L-glutamate 5-semialdehyde to N2-acetyl-L-ornithine as well as in catabolic reactions during growth on putrescine or 4-guanidinobutyrate but not during growth on arginine

661969