2.6.1.39: 2-aminoadipate transaminase

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For detailed information about 2-aminoadipate transaminase, go to the full flat file.

Reaction

Synonyms

2-aminoadipate aminotransferase, 2-aminoadipic aminotransferase, AAA-AT, AadAT, AAT, alpha-aminoadipate aminotransferase, alpha-aminoadipate aminotransferase (gene aro8), aminoadipate aminotransferase, aminoadipate aminotransferase/kynurenine aminotransferase II, Aro8, GKAT, glutamate-alpha-ketoadipate transaminase, glutamic-ketoadipic transaminase, halogenated tyrosine aminotransferase, KAT II/AADAT, kynurenine aminotransferase II, kynurenine aminotransferase II (EC 2.6.1.7), kynurenine/alpha-aminoadipate aminotransferase, More

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.39 2-aminoadipate transaminase

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Results	in table
1747	AA Sequence
2	Application
1	CAS Registry Number
9	Cloned(Commentary)
7	Cofactor
5	Crystallization (Commentary)
1	General Stability
23	Inhibitors
24	kcat/KM [mM/s]
49	KM Value [mM]
17	Localization
27	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
357	Organism
11	Pathway
58	PDB ID
8	pH Optimum
4	pH Range
2	pH Stability
4	Protein Variants
16	Purification (Commentary)
1	Reaction
1	Reaction Type
27	Reference
30	Source Tissue
17	Specific Activity [micromol/min/mg]
5	Storage Stability
81	Substrates and Products (Substrate)
15	Subunits
37	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
5	Temperature Stability [°C]
20	Turnover Number [1/s]

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Application on EC 2.6.1.39 - 2-aminoadipate transaminase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

medicine

Rattus norvegicus

Q64602

L-2-aminoadipate, the substrate for AadAT, is a well known astroglial-specific toxin, knowledge of the cerebral disposition of this compound is instrumental for the elucidation of its mechanism of toxicity and possible relevance in pathology

636625

pharmacology

Homo sapiens

Q8N5Z0

L-alpha-aminoadipate is a component of the precursor to penicillin and cephalosporin

639985