2.6.1.39: 2-aminoadipate transaminase

This is an abbreviated version!
For detailed information about 2-aminoadipate transaminase, go to the full flat file.

Word Map on EC 2.6.1.39

2.6.1.39

5'-phosphate

thermus

saccharopine

aminotransferases

thermophilus

transamination

dicarboxylic

semialdehyde

kynurenic

l-kynurenine

2-oxoadipate

l-lysine

pharmacology

medicine

Reaction

Synonyms

2-aminoadipate aminotransferase, 2-aminoadipic aminotransferase, AAA-AT, AadAT, AAT, alpha-aminoadipate aminotransferase, alpha-aminoadipate aminotransferase (gene aro8), aminoadipate aminotransferase, aminoadipate aminotransferase/kynurenine aminotransferase II, Aro8, GKAT, glutamate-alpha-ketoadipate transaminase, glutamic-ketoadipic transaminase, halogenated tyrosine aminotransferase, KAT II/AADAT, kynurenine aminotransferase II, kynurenine aminotransferase II (EC 2.6.1.7), kynurenine/alpha-aminoadipate aminotransferase, More

ECTree

2 Transferases

2.6 Transferring nitrogenous groups

2.6.1 Transaminases

2.6.1.39 2-aminoadipate transaminase

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Results	in table
1747	AA Sequence
2	Application
1	CAS Registry Number
9	Cloned(Commentary)
7	Cofactor
5	Crystallization (Commentary)
1	General Stability
23	Inhibitors
24	kcat/KM [mM/s]
49	KM Value [mM]
17	Localization
27	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
357	Organism
11	Pathway
58	PDB ID
8	pH Optimum
4	pH Range
2	pH Stability
4	Protein Variants
16	Purification (Commentary)
1	Reaction
1	Reaction Type
27	Reference
30	Source Tissue
17	Specific Activity [micromol/min/mg]
5	Storage Stability
81	Substrates and Products (Substrate)
15	Subunits
37	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
5	Temperature Stability [°C]
20	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 2.6.1.39 - 2-aminoadipate transaminase

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0.53

0.77

isoenzyme AadAT-I

1.5

kynurenine aminotransferase activity

1.56

10.68

isoenzyme AadAT-II

1102

substrate 2-oxoisovalerate, pH 7.5, 45°C

659885

2.65

Rattus norvegicus

kynurenine aminotransferase activity

636620, 639976

26.1

Rattus norvegicus

alpha-aminoadipate aminotransferase activity

636620, 639976

5079

Thermus thermophilus

substrate 2-oxoisocaproate, pH 7.5, 45°C

659885

513

Thermus thermophilus

substrate phenylpyruvate, pH 7.5, 45°C

659885

561

Thermus thermophilus

substrate 2-oxo-3-methylvalerate, pH 7.5, 45°C

659885

568

Thermus thermophilus

substrate pyruvate, pH 7.5, 45°C

659885

6.3

Rattus norvegicus

alpha-aminoadipate aminotransferase activity

636623

661

Thermus thermophilus

substrate oxaloacetate, pH 7.5, 45°C

659885

6788

Thermus thermophilus

substrate 2-oxoadipate, pH 7.5, 45°C

659885