2.6.1.44: alanine-glyoxylate transaminase

This is an abbreviated version!
For detailed information about alanine-glyoxylate transaminase, go to the full flat file.

Reaction

Synonyms

3-hydroxykynurenine transaminase, 3-hydroxykynurenine transaminase/alanine glyoxylate transaminase, AGT, AGT-Ma, AGT-Mi, AGT1, AGT2, AGX, AGXT, AGXT2, alanine aminotransferase, alanine glyoxalate transaminase 2, alanine glyoxylate aminotransferase, alanine-glyoxalate aminotransferase, alanine-glyoxalate transaminase 1, alanine-glyoxylate aminotransferase, alanine-glyoxylate aminotransferase 2, alanine-glyoxylate aminotransferase isoenzyme 2, alanine-glyoxylate aminotransferase-2, alanine-glyoxylic aminotransferase, alanine: glyoxylate aminotransferase, alanine:2-oxoglutarate aminotransferase, alanine:glyoxylate aminotransferase, alanine:glyoxylate aminotransferase 1, alanine:glyoxylate aminotransferase 2, alanine:glyoxylate aminotransferase type 1, alanine:glyoxylate aminotransferase/beta-alanine:pyruvate aminotransferase, aminotransferase 3, AT3, At3g08860, cytosolic alanine aminotransferase, D-AIB AT, EC 2.6.1.51, GGT, glyoxylate aminotransferase AGT1, L-alanine-glycine transaminase, L-alanine-glyoxylate aminotransferase, L-alanine:glyoxylate aminotransferase, More, serine pyruvate aminotransferase, serine:pyruvate/alanine:glyoxylate aminotransferase, SPT/AGT

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.44 alanine-glyoxylate transaminase

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Results	in table
6	Activating Compound
3685	AA Sequence
17	Application
1	CAS Registry Number
55	Cloned(Commentary)
38	Cofactor
13	Crystallization (Commentary)
482	Disease/ Diagnostics
3	Expression
32	General Information
5	General Stability
31	Inhibitors
46	kcat/KM [mM/s]
9	Ki Value [mM]
130	KM Value [mM]
87	Localization
61	Molecular Weight [Da]
37	Natural Substrates/ Products (Substrates)
119	Organism
1	Oxidation Stability
8	Pathway
52	PDB ID
26	pH Optimum
5	pH Range
2	pH Stability
5	pI Value
93	Protein Variants
33	Purification (Commentary)
4	Reaction
1	Reaction Type
115	Reference
2	Renatured (Commentary)
84	Source Tissue
17	Specific Activity [micromol/min/mg]
19	Storage Stability
167	Substrates and Products (Substrate)
52	Subunits
112	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
3	Temperature Range [°C]
5	Temperature Stability [°C]
68	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 2.6.1.44 - alanine-glyoxylate transaminase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-18°C, stable for about 2 weeks

Spinacia oleracea

-

640069

-20°C, 25 mM-potassium phosphate buffer, pH 7.5, containing 100 mM NaCl, 0.1 mM pyridoxal 5'-phosphate and 10% glycerol, my be stored for at least 3 months without loss of activity

Saccharomyces cerevisiae

-

640071

-20°C, 50 mM potassium phosphate buffer, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 4 weeks without loss of either activity

Rattus norvegicus

-

640067

-20�C, 50 mM potassium phosphate buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 4 weeks without loss of either activity

3 entries

-20°C, crude homogenate can be stored for 6-12 months with little loss of activity

Rattus norvegicus

-

640068

-20°C, peroxisomal apoenzyme, may be stored for at least 4 weeks without loss of activity

Gallus gallus

-

640074

-20°C, peroxisomal holoenzyme, may be stored for at least 4 weeks without loss of activity

Columba livia

-

640074

-20°C, purified enzyme, 50% glycerol, can be stored for at least 3 months with little loss in activity

Rattus norvegicus

-

640068

-20°C, purified enzyme, freezing results in formation of floculence and complete loss of activity

Rattus norvegicus

-

640068

-20°C, wild-type and mutant enzyme G82E are stable for at least 1 month

Homo sapiens

A2V838

684989

0-4°C, little or no activity is lost when stored for 2 weeks

Saccharomyces cerevisiae

-

640071

0-6�C, 50 mM potassium phosphate buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 2 weeks with little loss of either activity

4 entries

4°C, peroxisomal apoenzyme, 50% activity is lost when stored for 6 days

Gallus gallus

-

640074

4°C, peroxisomal holoenzyme, 50% activity is lost when stored for 6 days

Columba livia

-

640074

-20�C, 50 mM potassium phosphate buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 4 weeks without loss of either activity

Mus musculus

-

640067

-20�C, 50 mM potassium phosphate buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 4 weeks without loss of either activity

Canis lupus familiaris

-

640067

-20�C, 50 mM potassium phosphate buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 4 weeks without loss of either activity

Felis catus

-

640067

0-6�C, 50 mM potassium phosphate buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 2 weeks with little loss of either activity

Mus musculus

-

640067

0-6�C, 50 mM potassium phosphate buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 2 weeks with little loss of either activity

Rattus norvegicus

-

640067

0-6�C, 50 mM potassium phosphate buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 2 weeks with little loss of either activity

Canis lupus familiaris

-

640067

0-6�C, 50 mM potassium phosphate buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate, 1 mM 2-mercaptoethanol, may be stored for at least 2 weeks with little loss of either activity

Felis catus

-

640067