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2.6.1.5: tyrosine transaminase

This is an abbreviated version!
For detailed information about tyrosine transaminase, go to the full flat file.

Word Map on EC 2.6.1.5

Reaction

L-tyrosine
+
2-oxoglutarate
=
4-hydroxyphenylpyruvate
 +
L-glutamate

Synonyms

aminotransferase, tyrosine, At5g36160, At5g53970, beta-phenylalanine aminotransferase, glutamic phenylpyruvic aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, L-tyrosine-2-oxoglutarate aminotransferase, L-tyrosine: 2 oxoglutarate aminotransferase, L-tyrosine: 2-oxoglutarate aminotransferase, More, mTAT, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, PPY-AT, Sar2028, TAT, TAT1, TAT2, TAT3, TATase, TATc, Tyr aminotransferase, TyrAT, tyrosine aminotransferase, tyrosine-2-ketoglutarate aminotransferase, tyrosine-2-oxoglutarate aminotransferase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, VpAT

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.5 tyrosine transaminase

Substrates Products

Substrates Products on EC 2.6.1.5 - tyrosine transaminase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2-aminophenyl)alanine + 2-oxoglutarate
3-(4-aminophenyl)-2-oxopropanoate + L-glutamate
show the reaction diagram
-
10% of the activity that with L-tyrosine
-
?
(3-fluorophenyl)alanine + 2-oxoglutarate
3-(3-fluorophenyl)-2-oxopropanoate + L-glutamate
show the reaction diagram
-
4% of the activity that with L-tyrosine
-
?
(4-chlorophenyl)alanine + 2-oxoglutarate
3-(3-chlorophenyl)-2-oxopropanoate + L-glutamate
show the reaction diagram
-
17% of the activity with L-tyrosine
-
?
(4-fluorophenyl)alanine + 2-oxoglutarate
3-(4-fluorophenyl)-2-oxopropanoate + L-glutamate
show the reaction diagram
-
7.9% of the activity that with L-tyrosine
-
?
(R)-3-amino-5-methyl-hexanoic acid + 2-oxoglutarate
?
show the reaction diagram
relative activity: 48%
-
-
?
(S)-beta-phenylalanine + 2-oxoglutarate
3-oxo-3-phenylpropionic acid + L-glutamate
show the reaction diagram
relative activity: 100%
-
-
?
(S)-beta-phenylalanine + pyruvate
3-oxo-3-phenylpropionic acid + L-alanine
show the reaction diagram
the activity of VpAT with pyruvate is 85% of that with alpha-ketoglutarate as the amino acceptor
-
-
?
2-oxoglutarate + L-phenylalanine
L-glutamate + phenylpyruvate
show the reaction diagram
-
-
-
?
3,4-dihydroxyphenylalanine + 2-oxoglutarate
3-(3,4-dihydroxyphenyl)-2-oxopropanoate + L-glutamate
show the reaction diagram
3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamate
L-tyrosine + 2-oxoglutarate
show the reaction diagram
-
-
-
r
3-aminotyrosine + 2-oxoglutarate
3-(3-amino-4-hydroxyphenyl)-2-oxopropanoate + L-glutamate
show the reaction diagram
-
16% of the activity than with L-tyrosine
-
?
3-iodotyrosine + 2-oxoglutarate
3-(4-hydroxy-3-iodophenyl)-2-oxopropanoate + L-glutamate
show the reaction diagram
3-methoxytyrosine + 2-oxoglutarate
3-(3-methoxy-4-hydroxyphenyl)-2-oxopropanoate + L-glutamate
show the reaction diagram
-
22% of the activity with L-tyrosine
-
?
4-hydroxyphenylpyruvate + L-aspartate
L-tyrosine + oxaloacetate
show the reaction diagram
-
35% of the activity with L-glutamate
-
r
4-hydroxyphenylpyruvate + L-glutamate
L-tyrosine + 2-oxoglutarate
show the reaction diagram
4-hydroxyphenylpyruvate + L-phenylalanine
L-glutamate + phenylpyruvate
show the reaction diagram
-
-
-
?
4-methylthio-2-oxobutanoate + L-glutamate
?
show the reaction diagram
-
-
-
r
L-alanine + 2-oxoglutarate
pyruvate + L-glutamate
show the reaction diagram
L-alanine + 2-oxoisocaproate
pyruvate + 2-aminoisocaproate
show the reaction diagram
-
-
-
?
L-arginine + 2-oxoglutarate
?
show the reaction diagram
-
-
-
r
L-asparagine + 2-oxoglutarate
2-oxosuccinamate + L-glutamate
show the reaction diagram
L-aspartate + 2-oxoglutarate
oxaloacetate + L-glutamate
show the reaction diagram
L-cysteine + 2-oxoglutarate
3-mercapto-2-oxopropanoate + L-glutamate
show the reaction diagram
L-ethionine + 2-oxoglutarate
4-ethylsulfanyl-2-oxobutanoate + L-glutamate
show the reaction diagram
-
17% of the activity than with L-tyrosine
-
?
L-glutamate + 4-hydroxyphenylpyruvate
2-oxoglutarate + L-tyrosine
show the reaction diagram
L-glutamate + 4-hydroxyphenylpyruvate
L-tyrosine + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
L-glutamate + oxaloacetate
?
show the reaction diagram
-
-
-
-
r
L-glutamate + oxaloacetate
L-aspartate + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
L-glutamate + phenylpyruvate
2-oxoglutarate + L-phenylalanine
show the reaction diagram
L-glutamate + pyruvate
L-alanine + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
L-glutamine + 2-oxoglutarate
5-amino-2,5-dioxopentanoic acid + L-glutamate
show the reaction diagram
-
-
-
r
L-histidine + 2-oxoglutarate
3-(1H-imidazol-4-yl)-2-oxopropanoic acid + L-glutamate
show the reaction diagram
-
-
-
r
L-leucine + 2-oxoglutarate
4-methyl-2-oxopentanoic acid + L-glutamate
show the reaction diagram
-
-
-
r
L-methionine + 2-oxoglutarate
4-methylsulfanyl-2-oxobutanoate + L-glutamate
show the reaction diagram
L-phenylalanine + 2-oxoglutarate
2-oxo-3-phenylpropanoate + L-glutamate
show the reaction diagram
L-phenylalanine + 2-oxoglutarate
L-glutamate + phenylpyruvate
show the reaction diagram
-
-
-
-
?
L-phenylalanine + 2-oxoglutarate
phenylpyruvate + L-glutamate
show the reaction diagram
L-phenylalanine + pyruvate
phenylpyruvate + L-alanine
show the reaction diagram
-
-
-
r
L-serine + 2-oxoglutarate
3-hydroxy-2-oxopropanoic acid + L-glutamate
show the reaction diagram
-
-
-
r
L-tryptophan + 2-oxoglutarate
3-(1H-indol-3-yl)-2-oxopropanoate + L-glutamate
show the reaction diagram
L-tryptophan + oxaloacetate
3-(1H-indol-3-yl)-2-oxopropanoate + L-glycine
show the reaction diagram
-
-
-
-
?
L-tryptophan + pyruvate
3-(1H-indol-3-yl)-2-oxopropanoate + L-alanine
show the reaction diagram
L-tyrosine + 2-oxoglutarate
3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamate
show the reaction diagram
L-tyrosine + 2-oxoglutarate
4-hydroxyphenylpyruvate + L-glutamate
show the reaction diagram
L-tyrosine + 2-oxohexanoate
3-(4-hydroxyphenyl)-2-oxopropanoate + (2S)-2-aminohexanoate
show the reaction diagram
-
-
-
-
?
L-tyrosine + 2-oxopentanoate
3-(4-hydroxyphenyl)-2-oxopropanoate + (2S)-2-aminopentanoate
show the reaction diagram
relative activity compared to 2-oxoglutarate: 3%
-
-
?
L-tyrosine + 4-methylthio-2-oxobutanoate
?
show the reaction diagram
-
-
-
r
L-tyrosine + alpha-ketomethiobutyrate
?
show the reaction diagram
-
-
-
r
L-tyrosine + oxaloacetate
4-hydroxyphenylpyruvate + L-aspartate
show the reaction diagram
L-tyrosine + oxaloacetate
?
show the reaction diagram
relative activity compared to 2-oxoglutarate: 75%
-
-
?
L-tyrosine + phenylpyruvate
3-(4-hydroxyphenyl)-2-oxopropanoate + L-phenylalanine
show the reaction diagram
L-tyrosine + phenylpyruvate
4-hydroxyphenylpyruvate + L-phenylalanine
show the reaction diagram
L-tyrosine + prephenate
?
show the reaction diagram
relative activity compared to 2-oxoglutarate: 23%
-
-
?
L-tyrosine + pyruvate
4-hydroxyphenylpyruvate + L-alanine
show the reaction diagram
L-tyrosine + pyruvate
?
show the reaction diagram
relative activity compared to 2-oxoglutarate: 40%
-
-
?
oxaloacetate + L-glutamate
L-aspartate + 2-oxoglutarate
show the reaction diagram
-
-
-
r
phenylpyruvate + L-glutamate
2-oxoglutarate + L-phenylalanine
show the reaction diagram
-
-
-
r
rac-2-fluoro-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 15%
-
-
?
rac-2-methyl-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 5%
-
-
?
rac-3-bromo-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 53%
-
-
?
rac-3-chloro-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 56%
-
-
?
rac-3-fluoro-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 48%
-
-
?
rac-3-methyl-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 54%
-
-
?
rac-4-bromo-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 62%
-
-
?
rac-4-ethyl-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 134%
-
-
?
rac-4-fluoro-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 87%
-
-
?
rac-4-iso-propyl-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 61%
-
-
?
rac-4-methyl-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 100%
-
-
?
rac-4-nitro-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 32%
-
-
?
rac-4-nitro-hydroxy-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 61%
-
-
?
rac-4-propyl-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 126%
-
-
?
rac-4-trifluoromethyl-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 73%
-
-
?
rac-beta-leucine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 38%
-
-
?
rac-beta-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
relative activity: 100%
-
-
?
tryptophan + 2-oxoglutarate
3-indole-2-oxopropanoate + L-glutamate
show the reaction diagram
additional information
?
-