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2.6.1.64: glutamine-phenylpyruvate transaminase

This is an abbreviated version!
For detailed information about glutamine-phenylpyruvate transaminase, go to the full flat file.

Word Map on EC 2.6.1.64

Reaction

L-glutamine
+
phenylpyruvate
=
2-Oxoglutaramate
+
L-phenylalanine

Synonyms

cysteine conjugate beta-lyase/glutamine transaminase K, EC 2.6.1.14, EC 2.6.1.15, EC 2.6.1.7, Gln/phenylpyruvate transaminase, glutamic-oxaloacetic transaminase, glutamine transaminase K, glutamine transaminase L, glutamine transaminase-K, glutamine-phenylpyruvate aminotransferase, glutamine/phenylpyruvate transaminase, GOT1, GTK, histidine pyruvate aminotransferase isoenzyme 2, KAT/GTK, kynurenine aminotransferase/glutamine transaminase K

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.64 glutamine-phenylpyruvate transaminase

Substrates Products

Substrates Products on EC 2.6.1.64 - glutamine-phenylpyruvate transaminase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(-)allocystathionine + phenylpyruvate
? + L-phenylalanine
show the reaction diagram
-
-
-
-
r
4-cyano-L-alpha-aminobutyrate + glyoxylate
4-cyano-2-oxobutanoate + glycine
show the reaction diagram
-
-
-
-
r
4-cyano-L-alpha-aminobutyrate + phenylpyruvate
4-cyano-2-oxobutanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
r
5-S-L-cysteinyl-L-DOPA + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
-
-
-
?
5-S-L-cysteinyldopamine + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
transamination of 5 mM 5-S-Lcysteinyldopamine with 1 mM 4-(methylsulfanyl)-2-oxobutanoateat pH 7.4 is about 0.07% the rate at which the enzyme catalyzes transamination between 20 mM L-phenylalanine and 5 mM alpha-oxo-gamma-methiolbutyrate
-
-
?
albizziin + glyoxylate
3-carbamido-2-oxopropanoate + glycine
show the reaction diagram
-
-
-
-
r
CH3Hg-S-Cys + phenylpyruvate
? + L-phenylalanine
show the reaction diagram
-
-
-
-
?
Cys-S-Hg-S-Cys + phenylpyruvate
? + L-phenylalanine
show the reaction diagram
-
-
-
-
?
DL-2,6-diaminoheptanedioate + phenylpyruvate
2-amino-6-oxoheptanedioate + L-phenylalanine
show the reaction diagram
-
-
-
r
DL-homoserine + glyoxylate
4-hydroxy-2-oxobutanoate + glycine
show the reaction diagram
-
-
-
-
r
DL-homoserine + phenylpyruvate
4-hydroxy-2-oxobutanoate + phenylalanine
show the reaction diagram
DL-methionine-SR-sulfoximine + phenylpyruvate
4-methylsulfanyl-2-oxobutanoate-SR-sulfoximine + L-phenylalanine
show the reaction diagram
-
-
-
-
r
DL-penicillamine + phenylpyruvate
3-methyl-3-mercapto-2-oxo-butanoate + L-phenylalanine
show the reaction diagram
-
-
-
r
DL-threonine + phenylpyruvate
3-hydroxy-2-oxobutanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-3-(1-naphthyl)alanine + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
about 0.2% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
L-3-(2-naphthyl)alanine + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
about 0.5% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
L-5-N-hydroxyglutamine + phenylpyruvate
4-(N-hydroxycarbamoyl)-2-oxobutanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-5-N-methylglutamine + glyoxylate
4-(N-methylcarbamoyl)-2-oxobutanoate + glycine
show the reaction diagram
-
-
-
-
r
L-5-N-methylglutamine + phenylpyruvate
4-(N-methylcarbamoyl)-2-oxobutanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-arginine + pyruvate
5-guanidino-2-oxopentanoate + L-alanine
show the reaction diagram
-
-
-
-
r
L-asparagine + phenylpyruvate
2-oxosuccinamate + L-phenylalanine
show the reaction diagram
L-aspartate + pyruvate
oxaloacetate + L-alanine
show the reaction diagram
L-cystathionine + phenylpyruvate
S-(2-oxo-2-carboxyethyl)homocysteine + L-phenylalanine
show the reaction diagram
L-cysteine + glyoxylate
3-mercapto-2-oxopropanoate + glycine
show the reaction diagram
-
-
-
-
r
L-cysteine + phenylpyruvate
3-mercapto-2-oxopropanoate + L-phenylalanine
show the reaction diagram
L-cystine + phenylpyruvate
cystine ketimine + phenylalanine
show the reaction diagram
-
-
-
r
L-DOPA + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
about 0.02% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
L-ethionine + glyoxylate
4-ethylsulfanyl-2-oxobutanoate + glycine
show the reaction diagram
-
-
-
-
r
L-ethionine + phenylpyruvate
4-ethylsulfanyl-2-oxobutanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-gamma-glutamylhydrazone of glyoxylate + glyoxylate
?
show the reaction diagram
-
-
-
-
r
L-gamma-glutamylhydrazone of glyoxylate + phenylpyruvate
?
show the reaction diagram
-
-
-
-
r
L-gamma-glutamylhydrazone of phenylpyruvate + glyoxylate
?
show the reaction diagram
-
-
-
-
r
L-gamma-glutamylhydrazone of phenylpyruvate + phenylpyruvate
?
show the reaction diagram
-
-
-
-
r
L-glutamate + phenylpyruvate
2-oxoglutarate + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-glutamate-5-ethylester + phenylpyruvate
2-oxoglutarate-5-ethylester + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-glutamate-5-methylester + phenylpyruvate
2-oxoglutarate-5-methylester + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-glutamic acid-gamma-methyl ester + glyoxylate
2-oxo-pentandioate-5-methyl ester + glycine
show the reaction diagram
-
liver enzyme L
-
-
r
L-glutamic acid-gamma-methyl ester + phenylpyruvate
2-oxo-pentandioate-5-methyl ester + L-phenylalanine
show the reaction diagram
-
liver enzyme L
-
-
r
L-glutamine + 2-oxo-4-methiolbutyrate
2-oxoglutaramate + L-methionine
show the reaction diagram
-
-
-
-
r
L-glutamine + 2-oxo-4-methyl valerate
2-oxoglutaramate + L-4-methyl-norvaline
show the reaction diagram
-
-
-
-
r
L-glutamine + 2-oxobutyrate
2-oxoglutaramate + 2-aminobutanoate
show the reaction diagram
L-glutamine + 2-oxoglutaramate
2-oxoglutaramate + L-glutamine
show the reaction diagram
-
-
-
-
r
L-glutamine + 2-oxoglutarate
2-oxoglutaramate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-glutamine + 2-oxoisovalerate
2-oxoglutaramate + L-valine
show the reaction diagram
-
-
-
-
r
L-glutamine + 2-oxovalerate
2-oxoglutaramate + L-norvaline
show the reaction diagram
-
-
-
-
r
L-glutamine + 3-bromopyruvate
2-oxoglutaramate + 2-amino-3-bromopropionic acid
show the reaction diagram
-
-
-
-
r
L-glutamine + 3-hydroxypyruvate
2-oxoglutaramate + L-serine
show the reaction diagram
-
-
-
-
r
L-glutamine + 3-indolepyruvate
2-oxoglutaramate + L-tryptophan
show the reaction diagram
-
-
-
-
r
L-glutamine + 3-methyl-2-oxo-pentanoate
2-oxoglutaramate + L-3-methyl-norvaline
show the reaction diagram
-
-
-
-
r
L-glutamine + 4-methylsulfanyl-2-oxobutanoate
2-oxoglutaramate + L-methionine
show the reaction diagram
L-glutamine + alpha-keto-delta-carbamidovalerate
2-oxoglutaramate + L-arginine
show the reaction diagram
-
-
-
-
r
L-glutamine + alpha-keto-n-caproate
2-oxoglutaramate + L-norleucine
show the reaction diagram
-
-
-
-
r
L-glutamine + alpha-ketoisocaproate
2-oxoglutaramate + L-leucine
show the reaction diagram
-
-
-
-
r
L-glutamine + alpha-ketoisovalerate
2-oxoglutaramate + L-valine
show the reaction diagram
-
-
-
-
r
L-glutamine + glyoxylate
2-oxoglutaramate + glycine
show the reaction diagram
L-glutamine + oxaloacetate
2-oxoglutaramate + L-aspartate
show the reaction diagram
-
-
-
-
r
L-glutamine + p-hydroxyphenylpyruvate
2-oxoglutaramate + L-tyrosine
show the reaction diagram
-
-
-
-
r
L-glutamine + phenylpyruvate
2-oxoglutaramate + L-phenylalanine
show the reaction diagram
L-glutamine + pyruvate
2-oxoglutaramate + L-alanine
show the reaction diagram
L-glutamylmethylamide + glyoxylate
2-oxoglutarate-5-methylamide + glycine
show the reaction diagram
-
liver enzyme L
-
-
r
L-glutamylmethylamide + phenylpyruvate
2-oxoglutarate-5-methylamide + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-histidine + glyoxylate
3-(1H-imidazol-4-yl)-2-oxopropanoate + glycine
show the reaction diagram
-
-
-
-
r
L-histidine + phenylpyruvate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-histidine + pyruvate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-alanine
show the reaction diagram
L-homocysteine + phenylpyruvate
4-mercapto-2-oxobutanoate + L-phenylalanine
show the reaction diagram
-
-
-
r
L-homocystine + phenylpyruvate
? + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-kynurenine + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
about 23.6% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
L-kynurenine + pyruvate
4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine
show the reaction diagram
L-lanthionine + phenylpyruvate
2H-1,4-thiazine-5,6-dihydro-3,5-dicarboxylic acid + L-phenylalanine
show the reaction diagram
-
-
-
r
L-leucine + phenylpyruvate
4-methyl-2-oxopentanoate + L-phenylalanine
show the reaction diagram
L-methionine + 2-oxoglutaramate
L-glutamine + 4-methylsulfanyl-2-oxobutanoate
show the reaction diagram
-
isozymes L and K highly active
-
-
r
L-methionine + glyoxylate
4-methylsulfanyl-2-oxobutanoate + glycine
show the reaction diagram
-
-
-
-
r
L-methionine + phenylpyruvate
4-methylsulfanyl-2-oxobutanoate + L-phenylalanine
show the reaction diagram
L-methionine sulfone + glyoxylate
4-methylsulfonyl-2-oxobutanoate + glycine
show the reaction diagram
-
-
-
-
r
L-methionine sulfone + phenylpyruvate
4-methylsulfonyl-2-oxobutanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-methionine-SR-sulfoxide + glyoxylate
4-methylsulfinyl-2-oxobutanoate + glycine
show the reaction diagram
-
-
-
-
r
L-methionine-SR-sulfoxide + phenylpyruvate
4-methylsulfinyl-2-oxobutanoate + L-phenylalanine
show the reaction diagram
L-methionine-SR-sulfoximine + glyoxylate
4-methylsulfanyl-2-oxobutanoate-SR-sulfoximine + glycine
show the reaction diagram
-
-
-
-
r
L-methionine-SR-sulfoximine + phenylpyruvate
4-methylsulfanyl-2-oxobutanoate-SR-sulfoximine + L-phenylalanine
show the reaction diagram
-
-
-
-
r
L-norleucine + phenylpyruvate
2-oxohexanoate + L-phenylalanine
show the reaction diagram
-
-
-
r
L-phenylalanine + 2-oxoglutaramate
phenylpyruvate + L-glutamine
show the reaction diagram
-
-
-
-
r
L-phenylalanine + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
L-phenylalanine + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
-
-
-
?
L-phenylalanine + 4-(methylsulfanyl)-2-oxobutanoate
phenylpyruvate + L-methionine
show the reaction diagram
L-phenylalanine + 4-hydroxyphenylpyruvate
phenylpyruvate + L-tyrosine
show the reaction diagram
-
-
-
-
r
L-phenylalanine + 4-methylsulfanyl-2-oxobutanoate
phenylpyruvate + L-methionine
show the reaction diagram
L-phenylalanine + alpha-keto-n-caproate
phenylpyruvate + L-norleucine
show the reaction diagram
-
-
-
-
r
L-phenylalanine + alpha-keto-n-valerate
phenylpyruvate + L-norvaline
show the reaction diagram
-
-
-
-
r
L-phenylalanine + alpha-ketobutyrate
phenylpyruvate + 2-aminobutyrate
show the reaction diagram
-
-
-
-
r
L-phenylalanine + glyoxylate
phenylpyruvate + glycine
show the reaction diagram
-
-
-
-
r
L-phenylalanine + indolepyruvate
phenylpyruvate + L-tryptophan
show the reaction diagram
-
-
-
-
r
L-phenylalanine + pyruvate
phenylpyruvate + L-alanine
show the reaction diagram
L-serine + pyruvate
3-hydroxy-2-oxopropanoate + L-alanine
show the reaction diagram
-
-
-
-
r
L-threonine + pyruvate
3-hydroxy-2-oxobutanoate + L-alanine
show the reaction diagram
-
-
-
-
r
L-tryptophan + pyruvate
indolepyruvate + L-alanine
show the reaction diagram
-
-
-
-
r
L-tyrosine + 2-oxoglutaramate
3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamine
show the reaction diagram
L-tyrosine + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
about 9% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
L-tyrosine + glyoxylate
3(4-hydroxyphenyl)-2-oxopropanoate + glycine
show the reaction diagram
-
-
-
-
r
O-carbamoyl-L-serine + glyoxylate
O-carbamoyl-(3-hydroxy-2-oxo-propanoate) + glycine
show the reaction diagram
-
-
-
-
r
phenylpyruvate + L-alanine
L-phenylalanine + pyruvate
show the reaction diagram
-
-
-
-
r
phenylpyruvate + L-glutamine
?
show the reaction diagram
-
about 64% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
phenylpyruvate + L-leucine
?
show the reaction diagram
-
about 25% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
phenylpyruvate + L-methionine
?
show the reaction diagram
-
about 30% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
S-(1,1,2,2-tetrafluoroethyl)-L-cysteine + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
about 63% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
S-(1,2-dichlorovinyl)-L-cysteine + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
about 13% the rate exhibited with L-phenylalanine and alpha-oxo-gamma-methiolbutyrate
-
-
?
S-aminoethyl-L-cysteine + phenylpyruvate
2H-1,4-thiazine-5,6-dihydro-3-carboxylic acid + L-phenylalanine + H2O
show the reaction diagram
-
-
-
r
S-aminoethyl-L-cysteine + phenylpyruvate
S-aminoethyl-(3-mercapto-2-oxopropanoate) + L-phenylalanine
show the reaction diagram
-
-
-
-
r
S-aminomethyl-L-cysteine + phenylpyruvate
2H-1,4-thiazine-5,6-dihydro-3-carboxylic acid + L-phenylalanine
show the reaction diagram
-
-
-
-
?
S-carbamoyl-L-cysteine + glyoxylate
S-carbamoyl-3-mercapto-2-oxo-propanoate + glycine
show the reaction diagram
-
-
-
-
r
S-methyl-L-cysteine + glyoxylate
3-methylsulfanyl-2-oxopropanoate + glycine
show the reaction diagram
-
-
-
-
r
S-methyl-L-cysteine + phenylpyruvate
3-methylsulfanyl-2-oxopropanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
r
Se-methyl-L-selenocysteine + 4-(methylsulfanyl)-2-oxobutanoate
?
show the reaction diagram
-
-
-
-
?
additional information
?
-