2.6.1.75: cysteine-conjugate transaminase
This is an abbreviated version!
For detailed information about cysteine-conjugate transaminase, go to the full flat file.
Reaction
Synonyms
aminotransferase, cysteine conjugate, cysteine-conjugate alpha-ketoglutarate transaminase
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 2.6.1.75 - cysteine-conjugate transaminase
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REACTION DIAGRAM
S-(4-bromophenyl)-L-cysteine + 2-oxoglutarate
S-(4-bromophenyl)-3-thiopyruvate + L-glutamate
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highest activity with all three isoenzymes: CAT-I, CAT-IIA, CAT-IIB
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r
additional information
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isoenzyme CAT-I may be involved in in vivo transamination of cysteine conjugates in rat liver, value of reverse reaction is 5 times lower than forward reaction by CAT-I, forward and reverse reaction at similar rates for CAT-IIA and CAT-IIB
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