2.6.1.76: diaminobutyrate-2-oxoglutarate transaminase

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For detailed information about diaminobutyrate-2-oxoglutarate transaminase, go to the full flat file.

Reaction

Synonyms

(Pl)EctB, 2,4-diaminobutyrate 4-aminotransferase, 2,4-diaminobutyrate aminotransferase, DABA aminotransferase, DABA AT, DABA-AT, DABA:2-KG 4 aminotransferase, Diaminobutyrate transaminase, EctB, L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, L-diaminobutyric acid transaminase, More

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.76 diaminobutyrate-2-oxoglutarate transaminase

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Results	in table
7369	AA Sequence
13	Application
1	CAS Registry Number
11	Cloned(Commentary)
2	Cofactor
8	General Information
2	Inhibitors
6	kcat/KM [mM/s]
13	KM Value [mM]
3	Metals/Ions
8	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
18	Organism
11	Pathway
8	PDB ID
4	pH Optimum
1	pH Range
1	pI Value
14	Protein Variants
3	Purification (Commentary)
3	Reaction
1	Reaction Type
18	Reference
2	Source Tissue
1	Specific Activity [micromol/min/mg]
39	Substrates and Products (Substrate)
4	Subunits
20	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
6	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.6.1.76 - diaminobutyrate-2-oxoglutarate transaminase

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SYSTEMATIC NAME

IUBMB Comments

L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase

A pyridoxal-phosphate protein that requires potassium for activity [4]. In the proteobacterium Acinetobacter baumannii, this enzyme is cotranscribed with the neighbouring ddc gene that also encodes EC 4.1.1.86, diaminobutyrate decarboxylase. Differs from EC 2.6.1.46, diaminobutyrate---pyruvate transaminase, which has pyruvate as the amino-group acceptor. This is the first enzyme in the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.3.1.178, diaminobutyrate acetyltransferase and EC 4.2.1.108, ectoine synthase [3,4].