2.6.1.86: 2-amino-4-deoxychorismate synthase
This is an abbreviated version!
For detailed information about 2-amino-4-deoxychorismate synthase, go to the full flat file.
Word Map on EC 2.6.1.86
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2.6.1.86
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anthranilate
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ammonia
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phenazine
-
synthases
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amidotransferase
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enzyme-bound
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venezuelae
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aminodeoxychorismate
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chorismate-utilizing
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biotechnology
- 2.6.1.86
- anthranilate
- ammonia
- phenazine
- synthases
-
amidotransferase
-
enzyme-bound
- venezuelae
-
aminodeoxychorismate
-
chorismate-utilizing
- biotechnology
Reaction
Synonyms
2-amino-2-deoxyisochorismate (ADIC) synthase, 2-amino-2-deoxyisochorismate synthase, 2-amino-2desoxyisochorismate synthase, ADCS, ADIC synthase, aminodeoxyisochorismate synthase, PabA, PhzE, SgcD
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Reference
Reference on EC 2.6.1.86 - 2-amino-4-deoxychorismate synthase
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Morollo, A.A.; Bauerle, R.
Characterization of composite aminodeoxyisochorismate synthase and aminodeoxyisochorismate lyase activities of anthranilate synthase
Proc. Natl. Acad. Sci. USA
90
9983-9987
1993
Salmonella enterica subsp. enterica serovar Typhimurium
McDonald, M.; Mavrodi, D.V.; Thomashow, L.S.; Floss, H.G.
Phenazine biosynthesis in Pseudomonas fluorescens: branchpoint from the primary shikimate biosynthetic pathway and role of phenazine-1,6-dicarboxylic acid
J. Am. Chem. Soc.
123
9459-9460
2001
Pseudomonas fluorescens
Van Lanen, S.G.; Lin, S.; Shen, B.
Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolism
Proc. Natl. Acad. Sci. USA
105
494-499
2008
Streptomyces globisporus
Culbertson, J.E.; Toney, M.D.
Expression and characterization of PhzE from P. aeruginosa PAO1: aminodeoxyisochorismate synthase involved in pyocyanin and phenazine-1-carboxylate production
Biochim. Biophys. Acta
1834
240-246
2013
Pseudomonas aeruginosa (G3XCK6), Pseudomonas aeruginosa
Li, Q.A.; Mavrodi, D.V.; Thomashow, L.S.; Roessle, M.; Blankenfeldt, W.
Ligand binding induces an ammonia channel in 2-amino-2-desoxyisochorismate (ADIC) synthase PhzE
J. Biol. Chem.
286
18213-18221
2011
Burkholderia lata, Burkholderia lata 383
Culbertson, J.E.; Chung, D.h.; Ziebart, K.T.; Espiritu, E.; Toney, M.D.
Conversion of aminodeoxychorismate synthase into anthranilate synthase with Janus mutations: mechanism of pyruvate elimination catalyzed by chorismate enzymes
Biochemistry
54
2372-2384
2015
Escherichia coli (P00903)
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