2.6.1.B6: dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose transaminase
This is an abbreviated version!
For detailed information about dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose transaminase, go to the full flat file.
Reaction
Synonyms
DesI
ECTree
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Substrates Products
Substrates Products on EC 2.6.1.B6 - dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose transaminase
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REACTION DIAGRAM
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate
dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate
dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate
the enzyme is involved in biosynthesis of desosamine
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dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate
dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate
the two active sites of the enzyme are located in clefts at the subunit/subunit interface. Electron density corresponding to the bound product demonstrates a covalent bond between the amino group of the product and C-4' of the pyridoxal 5'-phosphate cofactor
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