2.7.1.105: 6-phosphofructo-2-kinase

This is an abbreviated version!
For detailed information about 6-phosphofructo-2-kinase, go to the full flat file.

Word Map on EC 2.7.1.105

2.7.1.105

2,6-bisphosphate

fructose-2,6-bisphosphate

pfkfb3

6-phosphofructo-1-kinase

camp-dependent

phosphofructokinase-1

mgatp

phosphoenzyme

medicine

sn-glycerol

cyclic-amp-dependent

fru-6-p

3-3hglucose

fbpase-2

pharmacology

diagnostics

drug development

Reaction

Synonyms

6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2, 6-phosphofructo kinase-2/fructose diphosphatase-2 isoenzyme 3, 6-phosphofructo-2-kinase, 6-phosphofructo-2-kinase/2,6-bisphosphatase 3, 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase:glucokinase complex, 6-phosphofructose 2-kinase, 6PF2K/Fru-2,6-P2ase, ATP:D-fructose-6-phosphate 2-phosphotransferase, fructose 6-phosphate 2-kinase, inducible 6-phosphofructo-2-kinase, iPFK2, kinase, 6-phosphofructo-2-(phosphorylating), OsF2KP1, OsF2KP2, Pfk-2, PFK-2/FBPase, PFK-2/FBPase-2, PFK2, PFK2/FBPase2, PFKFB, PFKFB-3, PFKFB1, PFKFB2, PFKFB3, PFKFB4, phosphofructokinase 2, phosphofructokinase-2, phosphofructokinase-2/fructose bisphosphatase-2, T-PFK2, tPFK-2, uPFK-2

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.105 6-phosphofructo-2-kinase

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Results	in table
11	Activating Compound
192	AA Sequence
18	Application
1	CAS Registry Number
56	Cloned(Commentary)
30	Cofactor
9	Crystallization (Commentary)
109	Disease/ Diagnostics
18	Expression
57	General Information
3	General Stability
24	IC50 Value
215	Inhibitors
75	Ki Value [mM]
189	KM Value [mM]
14	Localization
86	Metals/Ions
72	Molecular Weight [Da]
74	Natural Substrates/ Products (Substrates)
173	Organism
3	Pathway
33	PDB ID
32	pH Optimum
10	pH Range
3	pI Value
84	Posttranslational Modification
63	Protein Variants
54	Purification (Commentary)
60	Reaction
1	Reaction Type
158	Reference
1	Renatured (Commentary)
283	Source Tissue
48	Specific Activity [micromol/min/mg]
6	Storage Stability
265	Substrates and Products (Substrate)
60	Subunits
146	Synonyms
1	Systematic Name
45	Temperature Optimum [°C]
4	Temperature Stability [°C]
43	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 2.7.1.105 - 6-phosphofructo-2-kinase

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100000

3 entries

101000

Rattus norvegicus

high speed sedimentation equilibrium

102000

gel filtration

107000 - 109000

equilibrium sedimentation, sedimentation velocity analysis

110000

111000

2 * 60000, recombinant Tb1, SDS-PAGE, 2 * 111000, isozyme Tb1, about, sequence calculation

112500

gel filtration

118000

gel filtration

120000

132000

L-form, gel filtration

640315

140000

Trypanosoma brucei

Q52MQ5, Q6PY95

recombinant isozyme Tb1, gel filtration

661698

225000

Bos taurus

gel filtration

640304

250000

Saccharomyces cerevisiae

gel filtration

320000

gel filtration

33000

unfolded monomer, determined by gel filtration

370000

gel filtration

390000

H-form, gel filtration

49000

2 * 49000, SDS-PAGE

52000

2 * 52000, SDS-PAGE

53000

53900

2 * 53900, muscle-type isozyme, SDS-PAGE

94952

54000

5 entries

54760

Rattus norvegicus

2 * 54760, calculated from amino acid sequence

640291

55000

2 entries

55800

Pelophylax lessonae

2 * 55800, liver isoenzyme, SDS-PAGE

58000

60000

2 * 60000, recombinant Tb1, SDS-PAGE, 2 * 111000, isozyme Tb1, about, sequence calculation

661698

600000

Saccharomyces cerevisiae

gel filtration

61000

x * 61000, SDS-PAGE

66000

native protein, SDS-PAGE

693665

72000

Trypanosoma brucei

Q52MQ5, Q6PY95

x * 72000, isozyme Tb2, about, sequence calculation, x * 54000, isozyme Tb3, about, sequence calculation, x * 79000, isozyme Tb4, about, sequence calculation

76400

gel filtration

79000

x * 72000, isozyme Tb2, about, sequence calculation, x * 54000, isozyme Tb3, about, sequence calculation, x * 79000, isozyme Tb4, about, sequence calculation

83000

4 * 83000

85000 - 90000

gel filtration

89100

foetal liver, gel filtration

90000

90800

4 * 90800, SDS-PAGE

97000

gel filtration

98000

gel filtration

additional information

7 entries