2.7.1.105: 6-phosphofructo-2-kinase

This is an abbreviated version!
For detailed information about 6-phosphofructo-2-kinase, go to the full flat file.

Word Map on EC 2.7.1.105

2.7.1.105

2,6-bisphosphate

fructose-2,6-bisphosphate

pfkfb3

6-phosphofructo-1-kinase

camp-dependent

phosphofructokinase-1

mgatp

phosphoenzyme

medicine

sn-glycerol

cyclic-amp-dependent

fru-6-p

3-3hglucose

fbpase-2

pharmacology

diagnostics

drug development

Reaction

Synonyms

6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2, 6-phosphofructo kinase-2/fructose diphosphatase-2 isoenzyme 3, 6-phosphofructo-2-kinase, 6-phosphofructo-2-kinase/2,6-bisphosphatase 3, 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase:glucokinase complex, 6-phosphofructose 2-kinase, 6PF2K/Fru-2,6-P2ase, ATP:D-fructose-6-phosphate 2-phosphotransferase, fructose 6-phosphate 2-kinase, inducible 6-phosphofructo-2-kinase, iPFK2, kinase, 6-phosphofructo-2-(phosphorylating), OsF2KP1, OsF2KP2, Pfk-2, PFK-2/FBPase, PFK-2/FBPase-2, PFK2, PFK2/FBPase2, PFKFB, PFKFB-3, PFKFB1, PFKFB2, PFKFB3, PFKFB4, phosphofructokinase 2, phosphofructokinase-2, phosphofructokinase-2/fructose bisphosphatase-2, T-PFK2, tPFK-2, uPFK-2

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.105 6-phosphofructo-2-kinase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
11	Activating Compound
192	AA Sequence
18	Application
1	CAS Registry Number
56	Cloned(Commentary)
30	Cofactor
9	Crystallization (Commentary)
109	Disease/ Diagnostics
18	Expression
57	General Information
3	General Stability
24	IC50 Value
215	Inhibitors
75	Ki Value [mM]
189	KM Value [mM]
14	Localization
86	Metals/Ions
72	Molecular Weight [Da]
74	Natural Substrates/ Products (Substrates)
173	Organism
3	Pathway
33	PDB ID
32	pH Optimum
10	pH Range
3	pI Value
84	Posttranslational Modification
63	Protein Variants
54	Purification (Commentary)
60	Reaction
1	Reaction Type
158	Reference
1	Renatured (Commentary)
283	Source Tissue
48	Specific Activity [micromol/min/mg]
6	Storage Stability
265	Substrates and Products (Substrate)
60	Subunits
146	Synonyms
1	Systematic Name
45	Temperature Optimum [°C]
4	Temperature Stability [°C]
43	Turnover Number [1/s]

Purification

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Purification on EC 2.7.1.105 - 6-phosphofructo-2-kinase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Purification (commentary) Search

8 entries

2 distinct molecular forms

2 enzyme forms

2 isozymes, liver (L) and muscle (M) type

Pelophylax lessonae

94952

2 isozymes, partial

Saccharomyces cerevisiae

640320, 640321

adipose tissue

Rattus norvegicus

640342

by Cibacron blue-Sepharose and AMP-agarose chromatography

Escherichia coli

697948

from cytosol, 9000fold by ion exchange and affinity chromatography

gel filtration

gel filtration, recombinant protein

heart

liver

multiple molecular forms, predominant: H-(heavy) and L-(light)form

Spinacia oleracea

640315

mutant enzyme

2 entries

native enzyme from stock 427 by ion exchange and affinity chromatography, recombinant His-tagged wild-type and mutant isozyme Tb1 from Escherichia coli

partial

recombinant enzyme

recombinant enzymes

recombinant GST-tagged isozyme PFKFB3 from Escherichia coli strain BL21(DE3) by glutathione affinity chromatography

Homo sapiens

Q16875

729389

recombinant His6-tagged enzyme variants HBP1 and HBP2 and of mutant enzymes from Escherichia coli strain BL21(DE3) by nickel affinity and ion exchange chromatography, the tag is cleaved off, recombinant enzyme form HBP1 partially from Sf9 insect cells by affinity chromatography

Homo sapiens

Q16875

660814

recombinant wild-type and mutant enzymes from enzyme-deficient strain DF1020

skeletal muscle

wild-type and mutant enzyme

Bos taurus

640343