2.7.1.105: 6-phosphofructo-2-kinase

This is an abbreviated version!
For detailed information about 6-phosphofructo-2-kinase, go to the full flat file.

Reaction

Synonyms

6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2, 6-phosphofructo kinase-2/fructose diphosphatase-2 isoenzyme 3, 6-phosphofructo-2-kinase, 6-phosphofructo-2-kinase/2,6-bisphosphatase 3, 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase:glucokinase complex, 6-phosphofructose 2-kinase, 6PF2K/Fru-2,6-P2ase, ATP:D-fructose-6-phosphate 2-phosphotransferase, fructose 6-phosphate 2-kinase, inducible 6-phosphofructo-2-kinase, iPFK2, kinase, 6-phosphofructo-2-(phosphorylating), OsF2KP1, OsF2KP2, Pfk-2, PFK-2/FBPase, PFK-2/FBPase-2, PFK2, PFK2/FBPase2, PFKFB, PFKFB-3, PFKFB1, PFKFB2, PFKFB3, PFKFB4, phosphofructokinase 2, phosphofructokinase-2, phosphofructokinase-2/fructose bisphosphatase-2, T-PFK2, tPFK-2, uPFK-2

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.105 6-phosphofructo-2-kinase

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Results	in table
11	Activating Compound
192	AA Sequence
18	Application
1	CAS Registry Number
56	Cloned(Commentary)
30	Cofactor
9	Crystallization (Commentary)
109	Disease/ Diagnostics
18	Expression
57	General Information
3	General Stability
24	IC50 Value
215	Inhibitors
75	Ki Value [mM]
189	KM Value [mM]
14	Localization
86	Metals/Ions
72	Molecular Weight [Da]
74	Natural Substrates/ Products (Substrates)
173	Organism
3	Pathway
33	PDB ID
32	pH Optimum
10	pH Range
3	pI Value
84	Posttranslational Modification
63	Protein Variants
54	Purification (Commentary)
60	Reaction
1	Reaction Type
158	Reference
1	Renatured (Commentary)
283	Source Tissue
48	Specific Activity [micromol/min/mg]
6	Storage Stability
265	Substrates and Products (Substrate)
60	Subunits
146	Synonyms
1	Systematic Name
45	Temperature Optimum [°C]
4	Temperature Stability [°C]
43	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 2.7.1.105 - 6-phosphofructo-2-kinase

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TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

25

Arabidopsis thaliana

Q9MB58

about 76% of enzyme activity remains after 10 min, both in the absence and in the presence of phosphate

640338

4

Arabidopsis thaliana

Q9MB58

10 min, enzyme is stable, both in the absence and in the presence of phosphate

640338

42

Arabidopsis thaliana

Q9MB58

10 min, activation of enzyme and deletion mutant decreases rapidly, but the presence of phosphate protectes the enzyme activities from inactivation and 75% of enzyme activity remains after 15 min

640338

57

Rattus norvegicus

-

10 min, pH 7.1, progressive inactivation, phosphate does not protect

640288