2.7.1.113: deoxyguanosine kinase

This is an abbreviated version!
For detailed information about deoxyguanosine kinase, go to the full flat file.

Word Map on EC 2.7.1.113

2.7.1.113

deoxycytidine

mtdna

thymidine

hepatocerebral

deoxyribonucleoside

deoxynucleoside

ophthalmoplegia

sucla2

twinkle

9-beta-d-arabinofuranosylguanine

cladribine

c10orf2

nystagmus

2-chlorodeoxyadenosine

deoxyinosine

2.7.1.74

2-chloro-2'-deoxyadenosine

mngie

neurogastrointestinal

medicine

Reaction

Synonyms

(dihydroxypropoxymethyl)guanine kinase, 2'-deoxyguanosine kinase, deoxyadenosine kinase/deoxyguanosine kinase, deoxyguanosine kinase, DG kinase, DGK, dGKase, DGUOK, kinase, deoxyguanosine (phosphorylating), NTP-deoxyguanosine 5'-phosphotransferase, nucleoside triphosphate: deoxyguanosine 5'-phosphotransferase

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.113 deoxyguanosine kinase

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Results	in table
15	Activating Compound
771	AA Sequence
2	Application
1	CAS Registry Number
14	Cloned(Commentary)
33	Cofactor
2	Crystallization (Commentary)
334	Disease/ Diagnostics
2	Expression
9	General Information
9	General Stability
95	Inhibitors
5	kcat/KM [mM/s]
36	Ki Value [mM]
99	KM Value [mM]
32	Localization
47	Metals/Ions
13	Molecular Weight [Da]
39	Natural Substrates/ Products (Substrates)
59	Organism
5	Pathway
18	PDB ID
15	pH Optimum
5	pH Range
3	pH Stability
2	pI Value
42	Protein Variants
9	Purification (Commentary)
5	Reaction
1	Reaction Type
54	Reference
69	Source Tissue
19	Specific Activity [micromol/min/mg]
6	Storage Stability
175	Substrates and Products (Substrate)
8	Subunits
43	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
23	Turnover Number [1/s]

KM Value

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KM Value on EC 2.7.1.113 - deoxyguanosine kinase

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0.019

1-(2-deoxy-beta-D-ribofuranosyl)-7-iodoisocarbostyril

Homo sapiens

pH 7.6, 37°C, recombinant enzyme

662992

0.0026 - 0.5

2'-deoxyadenosine

9 entries

0.0006 - 0.123

2'-deoxyguanosine

20 entries

0.056

2-chloro-2'-arabino-fluoro-2'-deoxyadenosine

Homo sapiens

pH 7.6, recombinant mitochondrial deoxyguanosine kinase

640555

0.078

2-chloro-2'-deoxyadenosine

Homo sapiens

pH 7.6, recombinant mitochondrial deoxyguanosine kinase

640555

0.008 - 0.062

2-chlorodeoxyadenosine

2 entries

0.46

2-fluoro-arabinosyl-adenine

Homo sapiens

pH 7.6, recombinant mitochondrial deoxyguanosine kinase

640555

0.033

arabinosyl guanine

Homo sapiens

pH 7.6, recombinant mitochondrial deoxyguanosine kinase

640555

0.0085 - 3.3

ATP

22 entries

0.035

CTP

2 entries

0.206 - 2.689

deoxyadenosine

4 entries

0.34 - 4.424

deoxycytidine

2 entries

0.00032 - 0.76

deoxyguanosine

17 entries

0.012 - 0.021

deoxyinosine

2 entries

201.859

deoxythymidine

Xenopus laevis

Q6GPW6

at pH 8.0, temperature not specified in the publication

762058

10.624

deoxyuridine

Xenopus laevis

Q6GPW6

at pH 8.0, temperature not specified in the publication

762058

dioxolane guanosine

Homo sapiens

recombinant enzyme, pH 7.6, 37°C

661034

0.08 - 2.2

dTTP

3 entries

0.046

GTP

2 entries

0.092

Triphosphate

Homo sapiens

pH 7.5, 37°C

660855

0.006 - 0.125

UTP

3 entries

additional information

2 entries