2.7.1.137: phosphatidylinositol 3-kinase
This is an abbreviated version!
For detailed information about phosphatidylinositol 3-kinase, go to the full flat file.
Word Map on EC 2.7.1.137
-
2.7.1.137
-
wortmannin
-
mapks
-
mtor
-
rapamycin
-
erk
-
endothelial
-
pten
-
signal-regulated
-
pkc
-
metastasis
-
bcl-2
-
sirna
-
caspase-3
-
agonist
-
glycogen
-
leukemia
-
actin
-
pik3ca
-
phospholipase
-
insulin-like
-
mitogen
-
cyclins
-
integrins
-
tumorigenesis
-
irs-1
-
tensin
-
tnf
-
neuroprotective
-
c-jun
-
pi3-kinase
-
dominant-negative
-
adipocytes
-
nf-kappab
-
anti-apoptotic
-
insulin-stimulated
-
gtpases
-
insulin-induced
-
akt1
-
transwell
-
platelet-derived
-
rac1
-
kinase-3
-
igf-i
-
sh2
-
substrate-1
-
pleckstrin
-
grb2
-
egf-induced
-
everolimus
-
tyrosine-phosphorylated
-
drug development
-
medicine
-
pharmacology
- 2.7.1.137
- wortmannin
- mapks
- mtor
- rapamycin
- erk
- endothelial
- pten
-
signal-regulated
- pkc
- metastasis
- bcl-2
- sirna
- caspase-3
- agonist
- glycogen
- leukemia
- actin
- pik3ca
- phospholipase
-
insulin-like
-
mitogen
- cyclins
- integrins
- tumorigenesis
- irs-1
-
tensin
- tnf
-
neuroprotective
- c-jun
- pi3-kinase
-
dominant-negative
- adipocytes
- nf-kappab
-
anti-apoptotic
-
insulin-stimulated
- gtpases
-
insulin-induced
- akt1
-
transwell
-
platelet-derived
- rac1
- kinase-3
- igf-i
- sh2
- substrate-1
-
pleckstrin
- grb2
-
egf-induced
-
everolimus
-
tyrosine-phosphorylated
- drug development
- medicine
- pharmacology
Reaction
Synonyms
class 3 phosphatidylinositol 3-kinase vacuolar protein sorting 34, class I phosphoinositide 3-kinase, class III phosphatidylinositol 3-kinase, class III phosphoinositide 3-kinase, class III PI3K, HsC2-PI3K, hVps34, hVps34 PI 3-kinase, kinase (phosphorylating), phosphatidylinositol 3-, kinase, phosphatidylinositol 3- (phosphorylating), lipid kinase Vps34, mammalian vacuolar protein sorting 34 homologue, More, p110a, p110delta I PI3K., p110g-related PI 3-kinase, p85/p110 phosphoinositide 3-kinase, p85/p110 type phosphatidylinositol kinase, p85a phosphoinositide 3-kinase, phosphatidyl-inositol-3-kinase, phosphatidylinositide 3-kinase, phosphatidylinositide 3-kinase C2alpha, phosphatidylinositol 3 kinase, phosphatidylinositol 3'-kinase, phosphatidylinositol 3-kinase, phosphoinositide 3'-kinase, phosphoinositide 3-kinase, phosphoinositide 3-kinase Dp110, phosphoinositide 3-kinase gamma, phosphoinositide-3-kinase, PI 3-K, PI 3-kinase, PI-3-K, PI-3K, PI3 K, PI3 kinase, PI3-K, PI3-K-related protein MEC1, PI3-kinase, PI3K, PI3K type III, PI3Kalpha, PI3Kbeta, PI3Kgamma, PI3K_59F, PI3K_68D, PIK3, PIK3C3, protein sorting mutant 34 protein, PtdIns 3'-kinase, PtdIns 3-kinase, PtdIns 3-kinase vacuolar protein sorting 34, receptor-linked phosphatidylinositol 3-kinase, Rickettsia intracellular secreted kinase-1, Risk1, RT0135, TcVps34, type III phosphatidylinositol 3-kinase, vacuolar protein sorting 34, VPS34, Vps34p
ECTree
2.7.1.137 phosphatidylinositol 3-kinaseAdvanced search results
results (
results (Localization
Localization on EC 2.7.1.137 - phosphatidylinositol 3-kinase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
LOCALIZATION 
ORGANISM
UNIPROT
COMMENTARY 
GeneOntology No.
LITERATURE
SOURCE
-
in quiescent cells, PI3-kinase is distributed through the cytoplasm, although a portion is present in the nucleus, following stimulation with IL-1, PI3-kinase is redistributed, increasing in the nuclear compartment. PI3-kinase translocation to the nucleus upon IL-1R activation is an early event in IL-1 signaling mechanism, and may be involved in transcriptional activation
-
p110a is localized predominantly at the plasma membrane, while p110b and g is localized in the perinuclear region of the cells
-
-
PI3K complex localization during the elongation of the phagophor
colocalization with synaptic marker, synaptophysin at day 21 in vitro
additional information
-
the enzyme translocates onto liver endoplasmic reticulum
-
insulin-triggered mechanism of translocation of PI3K onto microsomes occurs in the liver of rats during refeeding
-
-
in quiescent cells, PI3-kinase is distributed through the cytoplasm, although a portion is present in the nucleus, following stimulation with IL-1, PI3-kinase is redistributed, increasing in the nuclear compartment. PI3-kinase translocation to the nucleus upon IL-1R activation is an early event in IL-1 signaling mechanism, and may be involved in transcriptional activation
-
in interchromatin domains, in stable association with inner nuclear matrix components
-
p110a is localized predominantly at the plasma membrane, while p110b and g is localized in the perinuclear region of the cells
-
the enzyme binds to the plasma membrane to get access to its lipid substrate phosphatidylinositol-4,5-bisphosphate, membrane binding via the C-terminal CAAX domain
additional information
-
PI3K associates with E-cadherin and part of the E-cadherin signaling complex, which is intergrated into the plasma membrane, complex formation, overview
-
additional information
-
enzyme and free or anchored glycosylated substrate meet in the submembrane space
-
additional information
Atg14 is present on autophagic isolation membranes
-
additional information
Atg14 is present on autophagic isolation membranes
-
additional information
-
PI3K associates with E-cadherin and part of the E-cadherin signaling complex, which is intergrated into the plasma membrane, complex formation, overview
-
additional information
-
UVRAG primarily associates with Rab9-positive endosomes
-
additional information
UVRAG primarily associates with Rab9-positive endosomes
-
additional information
UVRAG primarily associates with Rab9-positive endosomes
-
additional information
-
actin filaments facilitate the insulin-mediated association of the p85-p110 PI 3-kinase with glucose-transporter-containing compartments
-
additional information
the enzyme is secreted intracellularly in the host cell by Rickettsia typhi. Risk1 is present in both the pellet and supernatant of infected cells, implying that Risk1 is secreted into the host cell cytoplasm. Risk1 and Rab5 or EEA1 colocalization
-
additional information
-
the enzyme is secreted intracellularly in the host cell by Rickettsia typhi. Risk1 is present in both the pellet and supernatant of infected cells, implying that Risk1 is secreted into the host cell cytoplasm. Risk1 and Rab5 or EEA1 colocalization
-
additional information
-
the enzyme is secreted intracellularly in the host cell by Rickettsia typhi. Risk1 is present in both the pellet and supernatant of infected cells, implying that Risk1 is secreted into the host cell cytoplasm. Risk1 and Rab5 or EEA1 colocalization
-
-
additional information
-
the enzyme is secreted intracellularly in the host cell by Rickettsia typhi. Risk1 is present in both the pellet and supernatant of infected cells, implying that Risk1 is secreted into the host cell cytoplasm. Risk1 and Rab5 or EEA1 colocalization
-
-
