2.7.1.146: ADP-specific phosphofructokinase
This is an abbreviated version!
For detailed information about ADP-specific phosphofructokinase, go to the full flat file.
Word Map on EC 2.7.1.146
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2.7.1.146
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hyperthermophilic
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embden-meyerhof
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archaeon
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methanococcus
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jannaschii
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amp
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furiosus
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thermococcus
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atp-pfks
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phosphofructokinases
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ppi-dependent
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fructose-1,6-bisphosphate
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sulfate-reducing
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archaeoglobus
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fulgidus
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pyrophosphate-dependent
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zilligii
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thermococcales
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eucarya
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horikoshii
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adp-forming
- 2.7.1.146
-
hyperthermophilic
-
embden-meyerhof
- archaeon
-
methanococcus
- jannaschii
- amp
- furiosus
- thermococcus
- atp-pfks
-
phosphofructokinases
-
ppi-dependent
- fructose-1,6-bisphosphate
-
sulfate-reducing
-
archaeoglobus
- fulgidus
-
pyrophosphate-dependent
- zilligii
- thermococcales
- eucarya
- horikoshii
-
adp-forming
Reaction
Synonyms
ADP dependent phosphofructokinase, ADP-6-phosphofructokinase, ADP-dependent 6-phosphofructokinase, ADP-dependent glucokinase, ADP-dependent glucokinase/phosphofructokinase, ADP-dependent PFK, ADP-dependent phosphofructokinase, ADP-GK, ADP-Pfk, ancGK/PFK, AncMsPFK/GK, bifunctional ADP-dependent phosphofructokinase/glucokinase, MevePFK/GK, MJ1604, MjPFK/GK, MmazPFK/GK, MmPFK/GK, More, PFK, PFK-ADP, pfkC, PhPFK, TK0376, TLPFK
ECTree
Advanced search results
Engineering
Engineering on EC 2.7.1.146 - ADP-specific phosphofructokinase
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A71E
D17A
D433A
K158A
N15A
N160A
Q224A
Q97A
R185A
R191A
R191E
S183A
the mutant shows strongly increased kcat compared to the wild type enzyme
S183E
S189A
S263A
D17A
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the mutant shows severely decreased kcat compared to the wild type enzyme
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K158A
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the mutant shows slightly decreased kcat compared to the wild type enzyme
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N160A
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the mutant shows strongly increased kcat compared to the wild type enzyme
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R191A
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the mutant shows decreased kcat compared to the wild type enzyme
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S183A
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the mutant shows strongly increased kcat compared to the wild type enzyme
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E72A
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site-directed mutagenesis, the mutant shows reduced glucokinase and phosphofructokinase activities compared to wild-type enzyme
A71E
the mutant shows slightly decreased kcat compared to the wild type enzyme
D17A
the mutant shows severely decreased kcat compared to the wild type enzyme
production by site-directed mutagenesis, loss of PFK activity
K158A
the mutant shows slightly decreased kcat compared to the wild type enzyme
N15A
the mutant shows increased kcat compared to the wild type enzyme
N160A
the mutant shows strongly increased kcat compared to the wild type enzyme
Q224A
the mutant shows increased kcat compared to the wild type enzyme
Q97A
the mutant shows decreased kcat compared to the wild type enzyme
R191A
the mutant shows decreased kcat compared to the wild type enzyme
production by site-directed mutagenesis, the S183E mutant displays significantly less activity when the phosphoryl donor is replaced with IDP, UDP, GDP, or CDP compared with the wild type
S183E
the mutant displays significantly less activity when the phosphoryl donor ADP is replaced with IDP, UDP, GDP, or CDP, compared with the wild type
S189A
the mutant shows decreased kcat compared to the wild type enzyme
S263A
the mutant shows increased kcat compared to the wild type enzyme