2.7.1.148: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

This is an abbreviated version!
For detailed information about 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, go to the full flat file.

Word Map on EC 2.7.1.148

2.7.1.148

isoprenoids

mevalonate

isopentenyl

malaria

2-phosphate

antimalarial

dimethylallyl

plasmodium

non-mevalonate

jasmonate

drug development

1-deoxy-d-xylulose

terpenoids

nonhydrolyzable

solvent-mediated

mevalonate-independent

gametocytic

apicomplexan

water-mediated

2,4-cyclodiphosphate

2-hydroxyl

dmapp

medicine

Reaction

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

Synonyms

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase, 4-(cytidine-5-diphospho)-2-C-methyl-D-erythritol kinase, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, 4-diphosphocytidyl-2-C-methylerythritol 2-kinase, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-kinase, 4-diphosphocytidyl-2C-methyl-D-erythritol kinase, AaIspE, BsIspE, CcCMK1, CDP-ME, CDP-ME kinase, CDP-methylerythritol kinase, CDPME kinase, CDPMEK, CMK, EcIspE, GbCMK1, GbCMK2, IspDF, IspE, More, PvIspE, Ripening-associated protein pTOM41, TwCMK, YchB

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.148 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

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Results	in table
2	Activating Compound
35710	AA Sequence
5	Application
1	CAS Registry Number
13	Cloned(Commentary)
9	Cofactor
8	Crystallization (Commentary)
1	Expression
16	General Information
8	IC50 Value
19	Inhibitors
11	Ki Value [mM]
4	KM Value [mM]
5	Localization
16	Metals/Ions
6	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
128	Organism
7	Pathway
24	PDB ID
3	pH Optimum
4	pI Value
13	Protein Variants
10	Purification (Commentary)
5	Reaction
4	Reaction Type
27	Reference
4	Source Tissue
4	Specific Activity [micromol/min/mg]
33	Substrates and Products (Substrate)
5	Subunits
68	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Organism

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Organism on EC 2.7.1.148 - 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

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Agrobacterium tumefaciens

UniProt

UniProt

Bacillus subtilis 168

747328

P37550

UniProt

Bacillus subtilis DSM 23778

UniProt

UniProt

Escherichia coli DH5-alpha

UniProt

Mycobacterium tuberculosis

722218

P9WKG7

UniProt

Mycobacterium tuberculosis H37Rv

722218

P9WKG7

UniProt

Plasmodium vivax

clinical blood samples of Plasmodium vivax positive patients collected from seven malaria endemic geographical regions of India with entirely different topography viz. Delhi (New Delhi), Nadiad (Gujarat), Rourkela (Orissa), Goa (Goa), Mangaluru (Karnataka), Chennai (Tamil Nadu) and Sonapur (Assam)

762094

A5KAU8

UniProt

Plasmodium vivax Salvador I

UniProt

tomato

Uniprot

Thermus thermophilus HB8 / ATCC 27634 / DSM 579

662149

Tripterygium wilfordii

gene TwCMK

739765

Vitis vinifera x Vitis riparia

706809

Vitis vinifera x Vitis vinifera

706809

Yersinia pestis

721831