Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.7.1.149: 1-phosphatidylinositol-5-phosphate 4-kinase

This is an abbreviated version!
For detailed information about 1-phosphatidylinositol-5-phosphate 4-kinase, go to the full flat file.

Word Map on EC 2.7.1.149

Reaction

ATP
+
1-phosphatidyl-1D-myo-inositol 5-phosphate
=
ADP
 +
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate

Synonyms

1-phosphatidylinositol-4-phosphate 5-kinase, 1-phosphatidylinositol-4-phosphate kinase, 1-phosphatidylinositol-5-phosphate 4-kinase, Diphosphoinositide kinase, MSS4p, pan-phosphatidylinositol 5-phosphate 4-kinase, pan-PI5P4K, phosphatidylinositol 4-kinase, phosphatidylinositol 4-phosphate 5-kinase gamma, phosphatidylinositol 5 phosphate 4-kinase, phosphatidylinositol 5-phosphate 4-kinase, phosphatidylinositol 5-phosphate 4-kinase gamma, phosphatidylinositol 5-phosphate 4-kinase-alpha, phosphatidylinositol 5-phosphate, 4-kinase alpha, phosphatidylinositol 5-phosphate, 4-kinase beta, phosphatidylinositol phosphate kinase II gamma, phosphatidylinositol-5-phosphate 4-kinase, phosphatidylinositol-5-phosphate 4-kinase alpha, phosphatidylinositol-5-phosphate 4-kinase gamma, phosphatidylinositol-5-phosphate 4-kinase type II, phosphatidylinositol-5-phosphate 4-kinase type II beta, phosphatidylinositol-5-phosphate 4-kinase type-2 gamma, phosphatidylinositol-5-phosphate 4-kinase, type II, beta, PI-5-phosphate 4-kinase type II, PI4Kgamma5, PI4P-5 kinase, PI5P 4-kinase, PI5P4K, PI5P4Kalpha, PI5P4Kbeta, PI5P4Kgamma, PIP(4)K, PIP4K, PIP4K II, Pip4k2a, Pip4k2b, PIP4K2C, PIP4Kalpha, PIP4Kbeta, PIP4Kgamma, PIP4KIIalpha, PIP4KIIgamma, PIP5K2B, PIP5Kgamma, PIP5KII-alpha, PIP5KIII, PIPKII, PIPKIIalpha, PIPKIIbeta, PIPkinIIbeta, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PtdIns5P 4-kinase, PtdIns5P-4-kinase, PtdIns5P4-kinase, type II alpha phosphatidylinositol-5-phosphate 4-kinase, type II kinase, type II phosphatidylinositol 4-kinase, type II phosphatidylinositol 4-kinase beta, type II PI-5-P 4-kinase, type II PIP kinase, type II PtdIns 4-kinase, type II PtdIns 4-kinase beta, type IIbeta phosphatidylinositol 5-phosphate 4-kinase, type IIbeta PIPkin

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.149 1-phosphatidylinositol-5-phosphate 4-kinase

Source Tissue

Source Tissue on EC 2.7.1.149 - 1-phosphatidylinositol-5-phosphate 4-kinase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
isoform PI5P4Kbeta is expressed in neuronal populations, especially hippocampus and cortex
Manually annotated by BRENDA team
-
isoform PI5P4Kalpha localizes to white matter tracts, especially the corpus callosum
Manually annotated by BRENDA team
restricted expression in the thick ascending limb of the loop of Henle and in the intercalated cells of the collecting duct
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
-
isoform PI5P4Kbeta is expressed in neuronal populations, especially hippocampus and cortex
Manually annotated by BRENDA team
-
highest expression
Manually annotated by BRENDA team
-
both isoforms PI5P4Kalpha and PI5P4Kbeta are contained in axon terminals and dendritic spines adjacent to the synaptic membrane
Manually annotated by BRENDA team
-
quantitative real-time PCR enzyme expression analysis
Manually annotated by BRENDA team
-
inner segment
Manually annotated by BRENDA team
high mRNA expression
Manually annotated by BRENDA team
additional information