2.7.1.15: ribokinase
This is an abbreviated version!
For detailed information about ribokinase, go to the full flat file.
Word Map on EC 2.7.1.15
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2.7.1.15
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adp-dependent
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fructokinase
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glucokinases
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phosphopentomutase
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phosphofructokinase-2
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fructose-6-p
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ribose-binding
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diagnostics
- 2.7.1.15
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adp-dependent
- fructokinase
- glucokinases
- phosphopentomutase
- phosphofructokinase-2
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fructose-6-p
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ribose-binding
- diagnostics
Reaction
Synonyms
At1g17160, D-ribokinase, deoxyribokinase, Ms4585, rbk, RBSK, rbsK1, ribokinase, ribokinase (phosphorylating), Rv2436, Sa239
ECTree
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Substrates Products
Substrates Products on EC 2.7.1.15 - ribokinase
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REACTION DIAGRAM
ATP + 2-deoxy-D-ribitol
ADP + 2-deoxy-D-ribitol 5-phosphate
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41% of the activity with 2-deoxy-D-ribose
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?
dATP + D-ribose
dADP + D-ribose 5-phosphate
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108% of the activity with ATP
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?
dCTP + D-ribose
dCDP + D-ribose 5-phosphate
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25% of the activity with ATP
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-
?
dGTP + D-ribose
dGDP + D-ribose 5-phosphate
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50% of the activity with ATP
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?
GTP + D-ribose
GDP + D-ribose 5-phosphate
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32% of the activity with ATP
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?
ITP + D-ribose
IDP + D-ribose 5-phosphate
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37% of the activity with ATP
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?
ATP + 2-deoxy-D-ribose
ADP + 2-deoxy-D-ribose 5-phosphate
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75% of the activity with D-ribose
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?
ATP + 2-deoxy-D-ribose
ADP + 2-deoxy-D-ribose 5-phosphate
31% if the activity with D-ribose
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?
ATP + 2-deoxy-D-ribose
ADP + 2-deoxy-D-ribose 5-phosphate
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-
-
?
ATP + 2-deoxy-D-ribose
ADP + 2-deoxy-D-ribose 5-phosphate
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-
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?
ATP + 2-deoxy-D-ribose
ADP + 2-deoxy-D-ribose 5-phosphate
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first step in the inducible fermentation pathway for this sugar
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?
ATP + D-arabinose
ADP + D-arabinose 5-phosphate
0.74% if the activity with D-ribose
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-
?
ATP + D-arabinose
ADP + D-arabinose 5-phosphate
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4% if the activity with D-ribose
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?
ATP + D-ribose
ADP + D-ribose 5-phosphate
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?
ATP + D-ribose
ADP + D-ribose 5-phosphate
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?
ATP + D-ribose
ADP + D-ribose 5-phosphate
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highly specific for ribose phosphorylation
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?
ATP + D-ribose
ADP + D-ribose 5-phosphate
the enzyme catalyzes the first step of ribose metabolism
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?
ATP + D-ribose
ADP + D-ribose 5-phosphate
the enzyme catalyzes the first step of ribose metabolism
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?
ATP + D-ribose
ADP + D-ribose 5-phosphate
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?
CTP + D-ribose
CDP + D-ribose 5-phosphate
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18% of the activity with ATP
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?
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mutation of a gene encoding a putative ribokinase leads to reduced salt tolerance under potassium limitation in Bacillus subtilis
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additional information
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L-ribose and L-arabinose are not substrates for the recombinant enzyme
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?
additional information
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GTP displays activity, but at a level which was two orders of magnitude lower versus ATP
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?
additional information
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no significant phosphorylation of D-fructose, D-galactose and D-xylose
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additional information
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mycobacterial topoisomerase I (TopA) is found to physically interact with ribokinase both in vitro and in vivo. The interaction between ribokinase and topoisomerase I has opposite effects on their respective function. While the interaction between the two proteins inhibits the ability of topoisomerase I to relax supercoiled DNA, it stimulates ribokinase activity
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?
additional information
?
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mycobacterial topoisomerase I (TopA) is found to physically interact with ribokinase both in vitro and in vivo. The interaction between ribokinase and TopA has opposite effects on their respective function. While the interaction between the two proteins inhibits the ability of TopA to relax supercoiled DNA, it stimulates ribokinase activity
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?