2.7.1.166: 3-deoxy-D-manno-octulosonic acid kinase
This is an abbreviated version!
For detailed information about 3-deoxy-D-manno-octulosonic acid kinase, go to the full flat file.
Word Map on EC 2.7.1.166
-
2.7.1.166
-
influenzae
-
lipopolysaccharide
-
haemophilus
-
lps
-
pasteurella
-
lipooligosaccharide
-
kdo-lipid
-
chickens
-
heptosyltransferase
-
multocida
-
heptose
-
glycoforms
- 2.7.1.166
- influenzae
- lipopolysaccharide
-
haemophilus
- lps
-
pasteurella
- lipooligosaccharide
-
kdo-lipid
- chickens
-
heptosyltransferase
- multocida
-
heptose
-
glycoforms
Reaction
Synonyms
3-deoxy-D-manno-octulosonic acid kinase, KdkA, Kdo kinase, Kdo kinase A
ECTree
Advanced search results
Engineering
Engineering on EC 2.7.1.166 - 3-deoxy-D-manno-octulosonic acid kinase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
A112V
spontaneous KdkA mutant strain isolated from birds inoculated with high doses of a heptosyltransferase hptA mutant. The birds developed fowl cholera and the Pasteurella multocida isolates recovered from diseased birds no longer express truncated lipopolysaccharide. Mutation results in low level of enzymic acitivity
D193N
spontaneous KdkA mutant strain isolated from birds inoculated with high doses of a heptosyltransferase hptA mutant. The birds developed fowl cholera and the Pasteurella multocida isolates recovered from diseased birds no longer express truncated lipopolysaccharide. Mutation leads to complete loss of enzymic acitivity
H168Y
spontaneous KdkA mutant strain isolated from birds inoculated with high doses of a heptosyltransferase hptA mutant. The birds developed fowl cholera and the Pasteurella multocida isolates recovered from diseased birds no longer express truncated lipopolysaccharide. Residue is critical for Kdo kinase function and therefore glycoform A lipopolysaccharide assembly
R123P
spontaneous KdkA mutant strain isolated from birds inoculated with high doses of a heptosyltransferase hptA mutant. The birds developed fowl cholera and the Pasteurella multocida isolates recovered from diseased birds no longer express truncated lipopolysaccharide. Mutation is likely to have a significant impact on the secondary structure and probably affects the hinge action of the linker region