2.7.1.167: D-glycero-beta-D-manno-heptose-7-phosphate kinase
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For detailed information about D-glycero-beta-D-manno-heptose-7-phosphate kinase, go to the full flat file.
Reaction
Synonyms
bifunctional D-beta-D-heptose-7-phosphate kinase/D-beta-dheptose-1-phosphate adenylyltransferase, D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase, D-beta-D-heptose 7-phosphotransferase, D-beta-D-heptose-7-phosphate kinase, glycero-manno-heptose 7-phosphate kinase, heptose 7-phosphate kinase, HldE, HldE1 heptokinase
ECTree
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Systematic Name
Systematic Name on EC 2.7.1.167 - D-glycero-beta-D-manno-heptose-7-phosphate kinase
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ATP:D-glycero-beta-D-manno-heptose 7-phosphate 1-phosphotransferase
The bifunctional protein hldE includes D-glycero-beta-D-manno-heptose-7-phosphate kinase and D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase activity (cf. EC 2.7.7.70). The enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core in Gram-negative bacteria. The enzyme selectively produces D-glycero-beta-D-manno-heptose 1,7-bisphosphate [5].