2.7.1.169: pantoate kinase
This is an abbreviated version!
For detailed information about pantoate kinase, go to the full flat file.
Word Map on EC 2.7.1.169
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2.7.1.169
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phosphopantothenate
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thermococcus
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kodakarensis
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hyperthermophilic
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4'-phosphopantothenate
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pantothenate
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thermoplasmatales
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methanosarcina
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mazei
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picrophilus
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utp
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torridus
- 2.7.1.169
- phosphopantothenate
- thermococcus
- kodakarensis
-
hyperthermophilic
- 4'-phosphopantothenate
- pantothenate
- thermoplasmatales
-
methanosarcina
- mazei
-
picrophilus
- utp
- torridus
Reaction
Synonyms
COG1829, Mhun_0831, PoK, TK2141, TK2141 protein, TkPoK
ECTree
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General Information on EC 2.7.1.169 - pantoate kinase
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GENERAL INFORMATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
malfunction
the deletion mutant strain grows well in media supplemented with 1 mM CoA. The deletion mutant strain could not grow at all in the absence of CoA
metabolism
physiological function
coexpression of genes Mhun_0831 and Mhun_0832 complements the poor growth of the temperature-sensitive Escherichia coli pantothenate kinase mutant ts9. The recombinant Mhun_0831 and Mhun_0832 genes expressed in Escherichia coli cells exhibit pantoate kinase and phosphopantothenate synthetase activities, respectively
metabolism
the CoA biosynthesis pathway involves reactions that convert pantoate to 4'-phosphopantothenate. For this conversion, bacteria/eukaryotes commonly use two enzymes, pantothenate synthetase (PS) and pantothenate kinase (PanK). In the PS/PanK pathway, pantoate and beta-alanine are first condensed to form pantothenate by the reaction of PS, and then pantothenate is phosphorylated to generate 40-phosphopantothenate by the reaction of PanK
metabolism
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the CoA biosynthesis pathway involves reactions that convert pantoate to 4'-phosphopantothenate. For this conversion, bacteria/eukaryotes commonly use two enzymes, pantothenate synthetase (PS) and pantothenate kinase (PanK). In the PS/PanK pathway, pantoate and beta-alanine are first condensed to form pantothenate by the reaction of PS, and then pantothenate is phosphorylated to generate 40-phosphopantothenate by the reaction of PanK
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metabolism
-
the CoA biosynthesis pathway involves reactions that convert pantoate to 4'-phosphopantothenate. For this conversion, bacteria/eukaryotes commonly use two enzymes, pantothenate synthetase (PS) and pantothenate kinase (PanK). In the PS/PanK pathway, pantoate and beta-alanine are first condensed to form pantothenate by the reaction of PS, and then pantothenate is phosphorylated to generate 40-phosphopantothenate by the reaction of PanK
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