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2.7.1.172: protein-ribulosamine 3-kinase

This is an abbreviated version!
For detailed information about protein-ribulosamine 3-kinase, go to the full flat file.

Word Map on EC 2.7.1.172

Reaction

ATP
+
[protein]-N6-D-ribulosyl-L-lysine
=
ADP
+
[protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine

Synonyms

FN3K-related protein, FN3K-RP, Fn3KRP, fructosamine 3-kinase-related protein, fructosamine-3-kinase-related protein, fructosamine-3-kinase–related protein, ketosamine 3-kinase 2, ribulosamine/erythrulosamine 3-kinase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.172 protein-ribulosamine 3-kinase

Natural Substrates Products

Natural Substrates Products on EC 2.7.1.172 - protein-ribulosamine 3-kinase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + (R)-1-(5-(3-amino-4-hydroxy-3-methylbutyl)-1-methyl-1H-pyrrol-2-yl)-4-(p-tolyl)butan-1-one
ADP + (2R)-2-amino-2-methyl-4-(1-methyl)-5-[4-(4-methylphenyl)butanoyl]-1H-pyrrol-2-yl)butyl dihydrogen phosphate
show the reaction diagram
CS-0777
-
-
ir
ATP + [protein]-N6-D-psicosyl-L-lysine
ADP + [protein]-N6-(O3-phosphono-D-psicosyl)-L-lysine
show the reaction diagram
ketosamine-3-kinase 2 plays a role in freeing proteins from ribulosamines or psicosamines, which might arise in a several step process, from the reaction of amines with glucose and/or glycolytic intermediates. This role is shared by fructosamine-3-kinase (ketosamine-3-kinase 1), which has, in addition, the unique capacity to phosphorylate fructosamines
-
-
?
ATP + [protein]-N6-D-ribulosyl-L-lysine
ADP + [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine
show the reaction diagram
additional information
?
-