2.7.1.176: UDP-N-acetylglucosamine kinase

This is an abbreviated version!
For detailed information about UDP-N-acetylglucosamine kinase, go to the full flat file.

Reaction

Synonyms

epsilon/zeta toxin-antitoxin homologue, Ngzeta_1, ng_epsilon1 / ng_zeta1, ng_zeta1 toxin, PezT, TA homologue, toxin PezT, toxin zeta, UNAG kinase, zeta toxin, Zeta-toxin

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.176 UDP-N-acetylglucosamine kinase

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Results	in table
2	Activating Compound
1576	AA Sequence
1	Application
10	Cloned(Commentary)
7	Cofactor
3	Crystallization (Commentary)
22	General Information
1	General Stability
1	Inhibitors
6	kcat/KM [mM/s]
8	KM Value [mM]
5	Metals/Ions
6	Natural Substrates/ Products (Substrates)
12	Organism
1	pH Optimum
26	Protein Variants
6	Purification (Commentary)
1	Reaction
11	Reference
14	Substrates and Products (Substrate)
1	Subunits
24	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
6	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.7.1.176 - UDP-N-acetylglucosamine kinase

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SYSTEMATIC NAME

IUBMB Comments

ATP:UDP-N-acetyl-D-glucosamine 3'-phosphotransferase

Toxic component of a toxin-antitoxin (TA) module. The phosphorylation of UDP-N-acetyl-D-glucosamine results in the inhibition of EC 2.5.1.7, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, the first committed step in cell wall synthesis, which is then blocked. The activity of this enzyme is inhibited when the enzyme binds to the cognate epsilon antitoxin.