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2.7.1.183: glycoprotein-mannosyl O6-kinase

This is an abbreviated version!
For detailed information about glycoprotein-mannosyl O6-kinase, go to the full flat file.

Word Map on EC 2.7.1.183

Reaction

ATP
+
O3-[N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl/L-seryl-[protein]
=
ADP
+
O3-[N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-(6-phospho)mannosyl]-L-threonyl/L-seryl-[protein]

Synonyms

DrPOMK, HsPOMK, O-mannose kinase, POMK, protein kinase-like protein SgK196, protein O-mannose kinase, protein O-mannosyl kinase, protein-O-mannose kinase, SGK196, sugen kinase 196

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.183 glycoprotein-mannosyl O6-kinase

Disease

Disease on EC 2.7.1.183 - glycoprotein-mannosyl O6-kinase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Breast Neoplasms
N-glycosylated SGK196 suppresses the metastasis of basal-like breast cancer cells.
Muscular Dystrophies
SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function.
Neoplasm Metastasis
N-glycosylated SGK196 suppresses the metastasis of basal-like breast cancer cells.
Neoplasms
N-glycosylated SGK196 suppresses the metastasis of basal-like breast cancer cells.