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2.7.1.186: mevalonate-3-phosphate 5-kinase

This is an abbreviated version!
For detailed information about mevalonate-3-phosphate 5-kinase, go to the full flat file.

Reaction

ATP
+
(R)-3-phosphomevalonate
=
ADP
+
(R)-3,5-bisphosphomevalonate

Synonyms

M3P5K, MVA-3-P 5-kinase, Ta0762

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.186 mevalonate-3-phosphate 5-kinase

Cloned

Cloned on EC 2.7.1.186 - mevalonate-3-phosphate 5-kinase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
gene Ta0762, the pBAD-TacM plasmid series contains the genes of M3K, M3P5K, BMD, and IPK for the expression of part of modified MVA pathway II. Although the M3K, M3P5K, and IPK genes are derived from Thermoplasma acidophilum, various BMD genes have been utilized for plasmid construction. Recombinant expression of His-tagged enzyme in Escherichia coli strain BL21