2.7.1.191: protein-Npi-phosphohistidine-D-mannose phosphotransferase

This is an abbreviated version!
For detailed information about protein-Npi-phosphohistidine-D-mannose phosphotransferase, go to the full flat file.

Reaction

Synonyms

CD2775, D-glucosaminate PTS permease component EIIA, D-glucosaminate PTS permease component EIIB, D-glucosaminate PTS permease component EIIC, D-glucosaminate PTS permease component EIID, dgaABCD, EC 2.7.1.69, EII, EII man, EII(t)Man, EIIABCDman, EIIMan, EIItMan, EIItMan phosphotransferase system permease, enzyme II, Enzyme II Man, enzyme IIMan, glucose/mannose-phosphotransferase system permease, II-AMan, II-BMan, II-MMan, II-PMan, IIAB protein, IIABLMan, IIABMan, IIAMan, IIAmannose, IIBMan, IIBmannose, IICMan, IICmannose, IIDMan, IIDmannose, IIIMan, IIMan, Man-PTS, man-PTS EII, ManA, ManB, ManC, manL, manLMN, manN, mannose enzyme II, mannose family phosphotransferase system permease, mannose permease, mannose permease IID, mannose phosphotransferase system, mannose PTS, mannose PTS permease, mannose transporter, mannose-specific Enzyme II, mannose-specific phosphotransferase system component IID, mannose-specific PTS, mannosyl-1-phosphotransferase, ManPT, manR, ManX, manXYZ, ManY, ManZ, MptA, MptC, MptD, permease IIC, phosphoenolpyruvate-dependent phosphotransferase system, protein enzyme II, ptnABCD, PTS permease, ptsL pel/ptsM, ptsLPM, ptsM

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.191 protein-Npi-phosphohistidine-D-mannose phosphotransferase

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Results	in table
1	Activating Compound
7138	AA Sequence
7	Cloned(Commentary)
3	Expression
24	General Information
3	Inhibitors
2	kcat/KM [mM/s]
6	KM Value [mM]
16	Localization
15	Molecular Weight [Da]
31	Natural Substrates/ Products (Substrates)
75	Organism
4	Pathway
1	Posttranslational Modification
9	Protein Variants
1	Purification (Commentary)
1	Reaction
41	Reference
1	Storage Stability
57	Substrates and Products (Substrate)
12	Subunits
134	Synonyms
1	Systematic Name
2	Turnover Number [1/s]

Engineering

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Engineering on EC 2.7.1.191 - protein-Npi-phosphohistidine-D-mannose phosphotransferase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

H10C

Escherichia coli

-

the phosphorylation site mutant of subunit IIABMan is inactive

736390

H10C/H175C

Escherichia coli

-

the phosphorylation site mutant of subunit IIABMan is inactive

736390

H175C

Escherichia coli

-

the phosphorylation site mutant of subunit IIABMan is inactive

736390

H219Q

Escherichia coli

-

the phosphorylation site mutant of subunit IIABMan show less than 7% of wild type activity

736390

H86N

Escherichia coli

-

the phosphorylation site mutant of subunit IIABMan is inactive

736390

K48C

Escherichia coli

-

the phosphorylation site mutant of subunit IIABMan shows more than 50% of wild type activity

736390

S110C

Escherichia coli

-

the phosphorylation site mutant of subunit IIABMan shows more than 50% of wild type activity

736390

S72C

Escherichia coli

-

the phosphorylation site mutant of subunit IIABMan show less than 7% of wild type activity

736390

W12F

Escherichia coli

-

the phosphorylation site mutant of subunit IIABMan show less than 7% of wild type activity

736390