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2.7.1.2: glucokinase

This is an abbreviated version!
For detailed information about glucokinase, go to the full flat file.

Word Map on EC 2.7.1.2

Reaction

ATP
+
D-glucose
=
ADP
+
D-glucose 6-phosphate

Synonyms

ATP-dependent glucokinase, ATP-GLK, GK, GlcK, glk, Glk1, glucokinase (phosphorylating), glucokinase 1, kinase, gluco- (phosphorylating), KlGlk1, KLLA0C01155g, LmGlcK, NagC, NfGlck, SgGlkA, Sw0678, Sw2155, Sw3773, TcGlcK, TTE0090

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.2 glucokinase

Metals Ions

Metals Ions on EC 2.7.1.2 - glucokinase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CaCl2
MnCl2 yields 9% of the activity observed when MgCl2 is included in the assay
Cs+
52% of the activity compared to Mg2+
Fe2+
-
48% of the activation with Mg2+
KCl
-
at 20 mM
Li+
72% of the activity compared to Mg2+
MgCl2
the enzyme functions best when MgCl2 is included in the assay
MnCl2
MnCl2 yields 40% of the activity observed when MgCl2 is included in the assay
Na2MoO4
66% of the activity compared to Mg2+
Rb+
73% of the activity compared to Mg2+
additional information
CuCl2, CoCl2, ZnCl2 or CaCl2 have no appreciable effect on the enzyme activity