2.7.1.20: adenosine kinase
This is an abbreviated version!
For detailed information about adenosine kinase, go to the full flat file.
Word Map on EC 2.7.1.20
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2.7.1.20
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nucleoside
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deaminase
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purine
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amp
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adenylate
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inosine
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salvage
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hypoxanthine
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epilepsy
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phosphoribosyltransferase
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5'-nucleotidase
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5-iodotubercidin
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riboside
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deoxyadenosine
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s-adenosylhomocysteine
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deoxycytidine
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aicar
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anticonvulsant
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tubercidin
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dipyridamole
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neuromodulator
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ehna
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2\'-deoxycoformycin
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ecto-5\'-nucleotidase
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ribokinase
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erythro-9-2-hydroxy-3-nonyl
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adenosinergic
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6-methylmercaptopurine
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3hadenosine
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2-chloroadenosine
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coformycin
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nitrobenzylthioinosine
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epileptogenesis
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hypoxanthine-guanine
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transmethylation
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adenosine-induced
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hgprt
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kinase-deficient
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2'-deoxyadenosine
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adenosine-mediated
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3.5.4.4
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deoxycoformycin
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non-nucleoside
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analysis
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2.4.2.8
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9-beta-d-arabinofuranosyladenine
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n6-cyclopentyladenosine
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erythro-9-2-hydroxy-3-nonyladenine
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dado
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ara-a
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medicine
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diagnostics
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rephosphorylation
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pharmacology
- 2.7.1.20
- nucleoside
- deaminase
- purine
- amp
- adenylate
- inosine
-
salvage
- hypoxanthine
- epilepsy
-
phosphoribosyltransferase
- 5'-nucleotidase
- 5-iodotubercidin
- riboside
- deoxyadenosine
- s-adenosylhomocysteine
- deoxycytidine
- aicar
-
anticonvulsant
- tubercidin
- dipyridamole
-
neuromodulator
- ehna
-
2\'-deoxycoformycin
-
ecto-5\'-nucleotidase
- ribokinase
-
erythro-9-2-hydroxy-3-nonyl
-
adenosinergic
- 6-methylmercaptopurine
-
3hadenosine
- 2-chloroadenosine
- coformycin
-
nitrobenzylthioinosine
-
epileptogenesis
-
hypoxanthine-guanine
-
transmethylation
-
adenosine-induced
- hgprt
-
kinase-deficient
- 2'-deoxyadenosine
-
adenosine-mediated
-
3.5.4.4
- deoxycoformycin
-
non-nucleoside
- analysis
-
2.4.2.8
- 9-beta-d-arabinofuranosyladenine
-
n6-cyclopentyladenosine
-
erythro-9-2-hydroxy-3-nonyladenine
-
dado
- ara-a
- medicine
- diagnostics
-
rephosphorylation
- pharmacology
Reaction
Synonyms
adenosine kinase (phosphorylating), ADK, AdK-L, AdK-S, Ado kinase, AdoK, AK, ATP:adenosine 5'-phosphotransferase, CpAK, hADK, kinase, adenosine (phosphorylating), LdAdK, MGG_06270, Rv2202c, Tb927.6.2360, TbAK
ECTree
2.7.1.20 adenosine kinaseAdvanced search results
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results (Activating Compound
Activating Compound on EC 2.7.1.20 - adenosine kinase
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ACTIVATING COMPOUND 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
cyclophilin
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reversal of ADP-mediated aggregation of adenosine kinase by cyclophilin leads to its reactivation
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dihydroxyacetone phosphate
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10 mM, activity is stimulated more than 10fold
ATP
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0.7 mM with 0.5 mM Mg2+, 0.9 mM with 1 mM Mg2+ and 1.5 mM with 2 mM Mg2+
ATP
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required for phosphorylation of adenosine and N6-delta2-isopentenyl-adenosine
phosphate
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the degree of dependence varies among enzyme source and pH. At pH 6.2, complete dependence
phosphate
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the degree of dependence varies among enzyme source and pH. At pH 6.2, complete dependence
additional information
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the activity of both isozymes is increased by 1.5-3.5fold in case of increased methylation activity, e.g. during higher cell wall synthesis rates, apoptosis does not influence enzyme levels
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additional information
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salt stress induces the enzyme as well as the adenosine nucleosidase by 2 and 1.5fold, respectively, the enzyme responses to increased S-adenosyl-L-methionine-dependent methylation activity
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additional information
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no inhibition by phosphate, the activity in higher in phosphate buffer compared to HEPES buffer
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additional information
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no significant stimulation by O-phosphorylethanolamine, glucose 6-phosphate, D-3-phosphoglyceric acid, phospho-L-serine
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additional information
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the enzyme activity is increased in plants after inoculation with diverse RNA viruses or a germinivirus lacking an intact L2 protein
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additional information
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enzyme expression in increased due to pathogen infection or abiotic stresses
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additional information
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the activity of both isozymes is increased by 1.5-3.5fold in case of increased methylation activity, e.g. during highe cell wall synthesis rates or during xylogenesis
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additional information
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enzyme expression is increased 2-3fold in reponse to increased methylation activity, e.g. during salt stress and enhanced glycine betaine production
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