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2.7.1.201: protein-Npi-phosphohistidine-trehalose phosphotransferase

This is an abbreviated version!
For detailed information about protein-Npi-phosphohistidine-trehalose phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.201

Reaction

[protein]-Npi-phospho-L-histidine
+
alpha,alpha-trehalose[side 1]
=
[protein]-L-histidine
+
alpha,alpha-trehalose 6-phosphate[side 2]

Synonyms

EC 2.7.1.69, EIITre, enzyme IITre, IIBCTre, IITre, treB, trehalose phosphotransferase system, trehalose PTS permease, trehalose PTS transporter, trehalose(maltose)-specific PTS system components IIBC, trehalose-specific enzyme EIICBTre, trehalose-specific PTS enzyme II, treP

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.201 protein-Npi-phosphohistidine-trehalose phosphotransferase

Systematic Name

Systematic Name on EC 2.7.1.201 - protein-Npi-phosphohistidine-trehalose phosphotransferase

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SYSTEMATIC NAME
IUBMB Comments
protein-Npi-phospho-L-histidine:alpha,alpha-trehalose Npi-phosphotransferase
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.