2.7.1.207: protein-Npi-phosphohistidine-lactose phosphotransferase
This is an abbreviated version!
For detailed information about protein-Npi-phosphohistidine-lactose phosphotransferase, go to the full flat file.
Word Map on EC 2.7.1.207
-
2.7.1.207
-
symporter
-
cys
-
galactoside
-
kaback
-
single-cys
-
viii
-
proteoliposomes
-
polytopic
-
melibiose
-
downhill
-
inward-facing
-
sugar-binding
-
uphill
-
outward-facing
-
right-side-out
-
beta-galactoside
-
galactopyranoside
-
irreplaceable
-
methanethiosulfonate
-
mians
-
iiaglc
-
phosphoenolpyruvate-dependent
-
counterflow
-
lipid-dependent
-
phosphoenolpyruvate:sugar
-
brooker
-
galactopyranosyl
-
lactose-induced
-
charge-paired
-
whatsoever
-
electron-electron
-
six-helix
-
alpha-d-galactopyranoside
-
pope
-
phosphocarrier
-
homobifunctional
- 2.7.1.207
-
symporter
- cys
-
galactoside
-
kaback
-
single-cys
- viii
-
proteoliposomes
-
polytopic
- melibiose
-
downhill
-
inward-facing
-
sugar-binding
-
uphill
-
outward-facing
-
right-side-out
-
beta-galactoside
-
galactopyranoside
-
irreplaceable
-
methanethiosulfonate
-
mians
- iiaglc
-
phosphoenolpyruvate-dependent
-
counterflow
-
lipid-dependent
-
phosphoenolpyruvate:sugar
-
brooker
-
galactopyranosyl
-
lactose-induced
-
charge-paired
-
whatsoever
-
electron-electron
-
six-helix
-
alpha-d-galactopyranoside
-
pope
-
phosphocarrier
-
homobifunctional
Reaction
Synonyms
EC 2.7.1.69, EIICBLac, EIILac, enzyme II specific for lactose, Enzyme IIlac, IIALacS, IICBlac, lac-permease, lacE, lacEF, LACS, lactose permease, lactose PTS permease, lactose specific component of the PEP dependant phosphotransferase system, lactose transport protein, lactose transporter, lactose-specific Enzyme I1, lactose-specific enzyme II, lactose-specific permease enzyme IICB, lactose/galactose-specific permease, lacY, LacY permease, PTS 6CB, PTS 8C
ECTree
Advanced search results
Inhibitors
Inhibitors on EC 2.7.1.207 - protein-Npi-phosphohistidine-lactose phosphotransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
4-azidophenyl-beta-D-galactoside
-
irradiation of a reaction mixture containing 0.25 mM of photoactivatable 4-azidophenyl-beta-D-galactopyranoside and enzyme with UV light at 254 nm for 3 min causes approximately 90% loss of enzyme activity. When the photoinactivation experiments are carried out in the presence of 1 mM lactose, the loss of enzyme activity is significantly slowed
-
phosphotransferase protein IIAGlc
-
protein IIAGlc binding inhibits conformational dynamics of the enzyme and decreases binding affinity for sugar
-
-
substrates of the phosphotransferase system inhibit uptake of lactose. This inhibition is reversed by intravesicular (but not extravesicular) phosphoenolpyruvate. lactose uptake is also inhibited by enzyme IIIGlc preparations that are shocked into the vesicles, and this inhibition is reversed by phosphoenolpyruvate. Enzyme I and HPr neither inhibit nor stimulate lactose uptake
-
additional information
dephospho-IIAGlc inhibits the enzyme in the presence of glucose
-