2.7.1.22: ribosylnicotinamide kinase
This is an abbreviated version!
For detailed information about ribosylnicotinamide kinase, go to the full flat file.
Reaction
Synonyms
kinase, ribosylnicotinamide (phosphorylating), More, muscle-specific beta1 integrin binding protein, NadR, nicotinamide ribose kinase, nicotinamide riboside kinase, nicotinamide riboside kinase 1, nicotinamide riboside kinase 2, nicotinamide riboside kinase-2, NmR-K, NMRK1, NMRK2, NR kinase 1, Nrk, NRK-2, NRK1, Nrk2, Nrk2b
ECTree
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Engineering
Engineering on EC 2.7.1.22 - ribosylnicotinamide kinase
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D100A
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NRK2-D100A mutant protein does not accumulate appreciably, indicating that the mutant protein might be unstable
E98A
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NRK1-E98A mutant protein does not accumulate appreciably, indicating that the mutant protein might be unstable
additional information
generation of H6PDKO/NRK2 double KO mice. H6PDKO/NRK2 double KO mice do not display an exaggerated timing or severity of myopathy or overt change in mitochondrial metabolism despite depression of NAD+ availability. Metabolome analysis
additional information
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generation of H6PDKO/NRK2 double KO mice. H6PDKO/NRK2 double KO mice do not display an exaggerated timing or severity of myopathy or overt change in mitochondrial metabolism despite depression of NAD+ availability. Metabolome analysis
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additional information
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analysis of mutant strains for activities/functions of enzyme domains, reduced activity of class I mutants, overview