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2.7.1.23: NAD+ kinase

This is an abbreviated version!
For detailed information about NAD+ kinase, go to the full flat file.

Reaction

ATP
+
NAD+
=
ADP
+
NADP+

Synonyms

Afnk, AtNADK1, AtNADK2, AtNADK3, ATP: NAD(H) 2'-phosphotransferase, ATP:NAD 2'-phosphotransferase, ATP:NAD+ 2'-phosphotransferase, BsNADK, C5orf33, C5orf33 protein, diphosphopyridine nucleotide kinase, diphosphppyridine kinase, DPN kinase, EC 2.7.1.23, GmNADK1, GmNADK2, GmNADK3, GmNADK4, GmNADK5, HsNADK, kinase (phosphorylating), nicotinamide adenine dinucleotide, kinase, nicotinamide adenine dinucleotide (phosphorylating), MJ0917, NAD kinase, NAD kinase 1, NAD kinase 2, NAD kinase2, NAD(H) kinase, NadF, NADHK, NADK, NADK1, NADK2, NADK3, NADP phosphatase/NAD kinase, native plant calcium- and calmodulin-dependent NAD+-kinase, nicotinamide adenine dinucleotide kinase, OsNADK1, PH1074, Poly(P)/ATP NAD kinase , poly(P)/ATP-NAD kinase, poly(P)/ATPdependent NAD kinase, polyP/ATP-dependent NAD kinase, polyphosphate/ATP-NAD kinase, Pos5, Ppnk, PPNK_THEMA, sll1415, SlNADK1, SlNADK2, slr0040, slr0400, slr1415, SpNADK1, SpNADK2, styNadK, Utr, Utr1, Utr1p, YEF1, Yef1p, YfjB, YjbN, YtdI

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.23 NAD+ kinase

General Stability

General Stability on EC 2.7.1.23 - NAD+ kinase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
dialysis at 4°C for 18 h against buffer at pH 8.5 results in loss of 80% of the activity
-
liver enzyme can be dialyzed at 4°C for at least 16 h with loss of activity and is also stable towards freezing and thawing
-
liver preparation is unstable to dialysis and repeated freezing and thawing
-
partial loss of activity after freezing and thawing
-
stability is enhanced by immobilization on CNBr-activated Sepharose 4B
-
unstable, loses activity at room temperature overnight
-