2.7.1.30: glycerol kinase

This is an abbreviated version!
For detailed information about glycerol kinase, go to the full flat file.

Word Map on EC 2.7.1.30

2.7.1.30

glycerol-3-phosphate

triglyceride

adrenal

hypoplasia

dystrophy

muscular

adipose

3-phosphate

duchenne

lipase

phosphoenolpyruvate

hexokinase

x-linked

dihydroxyacetone

contiguous

adipocytes

triacylglycerols

carboxykinase

congenita

gluconeogenesis

glycerophosphate

lipolysis

hpr

iiaglc

1,6-bisphosphate

hypogonadism

co-immobilized

phosphocarrier

glyceroneogenesis

hypogonadotropic

glycosomes

dissimilation

triolein

1,3-propanediol

glucose-specific

aquaglyceroporins

d-glyceraldehyde

phosphoenolpyruvate:sugar

dhap

phosphoenolpyruvate-dependent

sn-glycerol-3-phosphate

sn-glycerol

drug development

diagnostics

synthesis

Reaction

Synonyms

AFUB_068560, ASTP , ATP-stimulated glucocorticoid-receptor translocation promoter , ATP: glycerol 3-phosphotransferase, ATP: glycerol-3-phosphotransferase, ATP:glycerol 3-phosphotransferase, ATP:glycerol 3-phosphotransferase , ATP:glycerol-3-phosphotransferase, GK, GK1, GK2, GK3, GK4, GK5, glcA, GLPK, glyceric kinase, glycerokinase, glycerol kinase, glycerol kinase 2, glycerol kinase 5, GLYK, GUT1, GYK, kinase, glycerol (phosphorylating), KpGlpK, More, slr1672, TbgGK, Tk-GK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.30 glycerol kinase

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Results	in table
22	Activating Compound
37954	AA Sequence
4	Application
1	CAS Registry Number
34	Cloned(Commentary)
2	Cofactor
23	Crystallization (Commentary)
918	Disease/ Diagnostics
8	Expression
52	General Information
10	General Stability
3	IC50 Value
150	Inhibitors
5	kcat/KM [mM/s]
2	Ki Value [mM]
123	KM Value [mM]
59	Localization
40	Metals/Ions
43	Molecular Weight [Da]
42	Natural Substrates/ Products (Substrates)
170	Organism
1	Oxidation Stability
5	Pathway
135	PDB ID
29	pH Optimum
12	pH Range
11	pH Stability
3	Posttranslational Modification
79	Protein Variants
37	Purification (Commentary)
13	Reaction
1	Reaction Type
168	Reference
124	Source Tissue
19	Specific Activity [micromol/min/mg]
10	Storage Stability
244	Substrates and Products (Substrate)
42	Subunits
85	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
2	Temperature Range [°C]
89	Temperature Stability [°C]
6	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 2.7.1.30 - glycerol kinase

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1,3-butanediol

activates

1,3-Propanediol

activates

1,4-Butanediol

activates

1-butanol

activates

1-Chloro-2-propanol

activates

1-propanol

2,3-Butanediol

activates

2-butanol

activates

2-Chloroethanol

activates

2-methyl-1-propanol

activates

2-Methyl-2-propanol

activates

2-Pentanol

activates

2-propanol

3-methyl-1-butanol

activates

Cyclohexanol

activates

Ethanediol methyl ether

activates

ethanol

activates

methanol

activates

Polyphosphate

addition of inorganic polyphosphate (PPin) inhibits or activates glycerol kinase due to the complexation of PPin with Mg2+ that shifts Mg2+ to ATP molar ratio below or to the optimum level

761883

rosiglitazone

Rattus norvegicus

rosiglitazone treatment markebly increases glycerol kinase mRNA expression in both the mesenteric and epididymal adipose tissues (1085.9% and 523.8% of the abundance in Long-Evans Tokushima Otsuka rats, respectively). The magnitude of glycerol kinase induced by rosiglitazone is significantly greater in the mesenteric fat than in the epididymal fat.

681755