2.7.1.33: pantothenate kinase
This is an abbreviated version!
For detailed information about pantothenate kinase, go to the full flat file.
Word Map on EC 2.7.1.33
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2.7.1.33
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neurodegeneration
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kinase-associated
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panks
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sign
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dystonia
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ganglia
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hallervorden-spatz
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extrapyramidal
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parkinsonism
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eye-of-the-tiger
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pla2g6
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phosphopantothenate
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dysarthria
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tiger
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neuroaxonal
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phosphopantetheine
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hypointensity
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medicine
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4'-phosphopantothenate
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pigmentary
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pantothenamide
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bradykinesia
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synthesis
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atp13a2
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4'-phosphopantetheine
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pantethine
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drug development
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neuroferritinopathy
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choreoathetosis
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phosphopantothenoylcysteine
- 2.7.1.33
- neurodegeneration
-
kinase-associated
-
panks
- sign
- dystonia
- ganglia
- hallervorden-spatz
-
extrapyramidal
- parkinsonism
-
eye-of-the-tiger
- pla2g6
- phosphopantothenate
- dysarthria
- tiger
-
neuroaxonal
- phosphopantetheine
-
hypointensity
- medicine
- 4'-phosphopantothenate
-
pigmentary
- pantothenamide
-
bradykinesia
- synthesis
-
atp13a2
- 4'-phosphopantetheine
- pantethine
- drug development
-
neuroferritinopathy
-
choreoathetosis
-
phosphopantothenoylcysteine
Reaction
Synonyms
4-phosphopantoate, BaPanK, Cab1, Cab1p, CoaA, coaW, CoaX, D-pantothenate kinase, EhPAnK, fumble, hPanK, hPanK1, hPANK2, hPanK3, hPanK4, HpPanK-III, HsPANK3, HsPANK4, kinase, pantothenate (phosphorylating), More, mPank, mPank1, mPanK2, mPanK3, MtCoaA, MtPanK, PAK, PanK, PanK-III, PanK1, PanK1alpha, PanK1b, PanK2, PanK3, PanK4, PanKBa, pantothenate kinase, pantothenate kinase 1, pantothenate kinase 2, pantothenate kinase 3, pantothenate kinase 4, pantothenate kinase-2, pantothenic acid kinase, PfPanK, Pfpank1, PoK, rPanK4, Rts protein
ECTree
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Subunits
Subunits on EC 2.7.1.33 - pantothenate kinase
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dimer
homodimer
additional information
?
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x * 48000, recombinant His/myc-tagged isozyme PanK2, SDS-PAGE, x * 63000, recombinant unprocessed PanK2, SDS-PAGE
dimer
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molecular mass, 30.8-61.2 kDa, of diverse protein variants expressed from different plasmids in different systems, SDS-PAGE and gel filtration, overview
dimer
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2 * 41100, isozyme Pank3, sequence calculation and gel filtration, 2 * 41600, isozyme Pank1beta, sequence calculation and gel filtration
homodimer
A0A167Z3Z6
the subunit of the homodimers is composed of two domains (domains I and II) and the binding cap (residues 153-173), with a dimerization interface along helix alpha6
homodimer
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the subunit of the homodimers is composed of two domains (domains I and II) and the binding cap (residues 153-173), with a dimerization interface along helix alpha6
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formation of a pantothenate kinase-ADP-pantothenate ternary complex, structure determination, pantothenate binding to the enzyme induces a significant conformational change in amino acids 243263, which form a lid that folds over the open pantothenate binding groove
additional information
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formation of a pantothenate kinase-ADP-pantothenate ternary complex, structure determination, pantothenate binding to the enzyme induces a significant conformational change in amino acids 243263, which form a lid that folds over the open pantothenate binding groove