2.7.1.36: mevalonate kinase
This is an abbreviated version!
For detailed information about mevalonate kinase, go to the full flat file.
Word Map on EC 2.7.1.36
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2.7.1.36
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fever
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autoinflammatory
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cholesterol
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isoprenoids
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mediterranean
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aciduria
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hereditary
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receptor-associated
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hyperimmunoglobulinemia
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vinyl
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ketone
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cryopyrin-associated
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phosphomevalonate
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febrile
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igd
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isopentenyl
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monogenic
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farnesyl
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tnfrsf1a
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isoprene
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hyper-igd
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anakinra
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rash
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lymphadenopathy
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hmg-coa
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inflammasome
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geranylgeranylation
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amyloidosis
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aphthous
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porokeratosis
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arthralgia
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non-sterol
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pyoderma
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nod2
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papa
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autoinflammation
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gangrenosum
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canakinumab
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adenitis
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pstpip1
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hyperimmunoglobulin
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medicine
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hepatosplenomegaly
-
cholesterogenesis
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etanercept
-
cryopyrin
-
synthesis
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diagnostics
- 2.7.1.36
- fever
- autoinflammatory
- cholesterol
-
isoprenoids
-
mediterranean
- aciduria
- hereditary
-
receptor-associated
- hyperimmunoglobulinemia
-
vinyl
- ketone
-
cryopyrin-associated
- phosphomevalonate
-
febrile
- igd
-
isopentenyl
-
monogenic
-
farnesyl
-
tnfrsf1a
- isoprene
-
hyper-igd
-
anakinra
- rash
- lymphadenopathy
- hmg-coa
- inflammasome
-
geranylgeranylation
- amyloidosis
-
aphthous
- porokeratosis
- arthralgia
-
non-sterol
-
pyoderma
- nod2
- papa
- autoinflammation
- gangrenosum
-
canakinumab
- adenitis
-
pstpip1
-
hyperimmunoglobulin
- medicine
-
hepatosplenomegaly
-
cholesterogenesis
-
etanercept
-
cryopyrin
- synthesis
- diagnostics
Reaction
Synonyms
ATP: mevalonate 5-phosphotransferase, ATP:mevalonate 5-phosphotransferase, GbMVK, kinase, mevalonate (phosphorylating), mevalonate 5-phosphotransferase, mevalonate phosphokinase, mevalonic acid kinase, mevalonic kinase, MmMK, MVA kinase, MVK, SSO0383, TcMVK, TeMVK
ECTree
2.7.1.36 mevalonate kinaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 2.7.1.36 - mevalonate kinase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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100% activity with ATP
-
-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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involved in isopentenyl diphosphate synthesis
-
-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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involved in cholesterol synthesis
-
-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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involved in cholesterol synthesis, decreased enzyme activity involved in mevalonic aciduria and hyperimmunoglobulin D syndrome
-
-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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a step in the production of farnesyldiphosphate and geranylgeranyl diphosphate, overview
-
-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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involved in cholesterol synthesis
-
-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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involved in cholesterol, steroid hormones und terpenoids synthesis
-
-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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a step in the mevalonate pathway, overview
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-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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involved in isopentenyl diphosphate synthesis
-
-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
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the enzyme catalyzes a step in the isoprenoid biosynthetic pathway via the essential intermediate 5-diphosphomevalonate
-
-
?
ATP + (R)-mevalonate
ADP + (R)-5-phosphomevalonate
-
-
-
?
ATP + mevalonate
ADP + phosphomevalonate
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via mevalonate pathway involved in isoprenoid biosynthesis
-
?
ATP + mevalonate
ADP + phosphomevalonate
-
mevalonate kinase is probably involved in regulation of cholesterol biosynthesis
-
?
ATP + mevalonate
ADP + phosphomevalonate
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part of the cholesterol and nonsterol isoprene biosynthetic pathway
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?
ATP + mevalonate
ADP + phosphomevalonate
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involved in mevalonate pathway of terpenoid biosynthesis
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?
ATP + mevalonate
ADP + phosphomevalonate
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enzyme may play a key role in regulating cholesterol biosynthesis
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?
additional information
?
-
-
mevalonate kinase is directly involved in regulation of luteinizing hormone receptor expression
-
-
?
additional information
?
-
-
the enzyme catalyzes a step in the isoprenoid biosynthetic pathway, which leads to a huge number of compounds that play important roles in plant growth and development
-
-
?
additional information
?
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the enzyme is involved in the modified mevalonate pathway. The recombinant protein is active. However in vitro conversion of the intermediates in the classical and modified pathways by cell-free extract from Sulfolobus solfataricus indicates that only the classical pathway likely works in the organism
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-
?
additional information
?
-
-
the enzyme is involved in the modified mevalonate pathway. The recombinant protein is active. However in vitro conversion of the intermediates in the classical and modified pathways by cell-free extract from Sulfolobus solfataricus indicates that only the classical pathway likely works in the organism
-
-
?
additional information
?
-
the enzyme is involved in the modified mevalonate pathway. The recombinant protein is active. However in vitro conversion of the intermediates in the classical and modified pathways by cell-free extract from Sulfolobus solfataricus indicates that only the classical pathway likely works in the organism
-
-
?
