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2.7.1.39: homoserine kinase

This is an abbreviated version!
For detailed information about homoserine kinase, go to the full flat file.

Word Map on EC 2.7.1.39

Reaction

ATP
+
L-homoserine
=
ADP
 +
O-phospho-L-homoserine

Synonyms

CglThrB, CThrB, DMR1, homoserine kinase, homoserine kinase (phosphorylating), HSK, kinase (phosphorylating), homoserine, kinase, homoserine (phosphorylating), Thr1, Thr1p, ThrB

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.39 homoserine kinase

KM Value

KM Value on EC 2.7.1.39 - homoserine kinase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3.8
4-hydroxynorvaline
-
pH 7.8
0.0676 - 2.7
ATP
31.8
D-homoserine
-
wild-type enzyme
11.6
L-2-amino-1,4-butanediol
-
wild-type enzyme
1.1
L-2-amino-5-hydroxyvalerate
-
wild-type enzyme
0.28
L-aspartate beta-semialdehyde
-
wild-type enzyme
0.58
L-aspartate semialdehyde
-
pH 7.8
0.087 - 58.2
L-homoserine
1.9
L-homoserine ethyl ester
-
wild-type enzyme
6.9
L-homoserine isobutyl ester
-
wild-type enzyme
1.2
L-homoserine isopropyl ester
-
wild-type enzyme
4.9
L-homoserine methyl ester
-
wild-type enzyme
5.8
L-homoserine n-butyl ester
-
wild-type enzyme
3.5
L-homoserine n-propyl ester
-
wild-type enzyme