2.7.1.48: uridine/cytidine kinase

This is an abbreviated version!
For detailed information about uridine/cytidine kinase, go to the full flat file.

Word Map on EC 2.7.1.48

2.7.1.48

thymidine

salvage

uracil

phosphoribosyltransferase

phosphorylase

orotate

ump

5-fluorouracil

5-fluorouridine

deoxycytidine

5-azacytidine

6-azauridine

3-deazauridine

orotidine

pyrazofurin

medicine

5-fluoro-2'-deoxyuridine

3huridine

dihydrouracil

drug development

diagnostics

biotechnology

Reaction

Synonyms

ATP:uridine 5'-phosphotransferase, hsUCK2, kinase, uridine (phosphorylating), More, pyrimidine ribonucleoside kinase, ttCK, UCK, UCK1, UCK2, UCKL1, Udk, UK/UPRT1, uridine cytidine kinase 2, uridine kinase, uridine phosphokinase, uridine-cytidine kinase, uridine-cytidine kinase 2, uridine/cytidine kinase, uridine/cytidine kinase 2

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.48 uridine/cytidine kinase

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Results	in table
3	Activating Compound
21722	AA Sequence
8	Application
1	CAS Registry Number
24	Cloned(Commentary)
13	Cofactor
7	Crystallization (Commentary)
298	Disease/ Diagnostics
3	Expression
39	General Information
7	General Stability
12	IC50 Value
64	Inhibitors
36	kcat/KM [mM/s]
8	Ki Value [mM]
92	KM Value [mM]
6	Localization
49	Metals/Ions
19	Molecular Weight [Da]
68	Natural Substrates/ Products (Substrates)
167	Organism
7	Pathway
48	PDB ID
19	pH Optimum
1	pH Range
1	pH Stability
44	Protein Variants
25	Purification (Commentary)
7	Reaction
1	Reaction Type
62	Reference
102	Source Tissue
13	Specific Activity [micromol/min/mg]
12	Storage Stability
272	Substrates and Products (Substrate)
21	Subunits
71	Synonyms
1	Systematic Name
17	Temperature Optimum [°C]
8	Temperature Stability [°C]
32	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 2.7.1.48 - uridine/cytidine kinase

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0.09

5-propyl-2'-deoxyuridine

Entamoeba histolytica

C4M4T4

706070

0.054

6-(4-hexyloxyanilino)uracil

Entamoeba histolytica

C4M4T4

706070

0.0003214

alpinetin

Homo sapiens

Q9BZX2

at 37°C, pH not specified in the publication

739129

0.031

ATP

Homo sapiens

Q9BZX2

pH 8.5, temperature not specified in the publication

758919

0.00000003463

CTP

Homo sapiens

Q9BZX2

at 37°C, pH not specified in the publication

739129

0.0006181

flavokawain B

Homo sapiens

Q9BZX2

at 37°C, pH not specified in the publication

739129

250

KCl

Entamoeba histolytica

C4M4T4

706070

0.0189 - 0.048

N-(3,5-dimethylphenyl)-2-[([5-[(4-fluorophenyl)methyl]-7-oxo-2,5,6,7-tetrahydro-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]methyl)sulfanyl]acetamide

2 entries

0.0092 - 0.0166

N-(4-bromophenyl)-2-[[1-(4-fluorophenyl)-4-hydroxy-1H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl]acetamide

2 entries

0.05

uridine

Homo sapiens

Q9BZX2

pH 8.5, temperature not specified in the publication

758919